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Related Concept Videos

Metal-Ligand Bonds02:51

Metal-Ligand Bonds

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The hemoglobin in the blood, the chlorophyll in green plants, vitamin B-12, and the catalyst used in the manufacture of polyethylene all contain coordination compounds. Ions of the metals, especially the transition metals, are likely to form complexes.
In these complexes, transition metals form coordinate covalent bonds, a kind of Lewis acid-base interaction in which both of the electrons in the bond are contributed by a donor (Lewis base) to an electron acceptor (Lewis acid). The Lewis acid in...
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Complexation Equilibria: Factors Influencing Stability of Complexes01:09

Complexation Equilibria: Factors Influencing Stability of Complexes

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In complexation reactions, metal cations are the electron pair acceptors, and the ligands are the electron pair donors. The stability of the metal complexes depends primarily on the complexing ability of the central metal ion and the nature of the ligands. Generally, the complexing ability of the metal ion depends on the size and charge of the ion. As the metal ion size increases, the stability of the metal complexes decreases, provided that the valency of the metal ion and the ligands remain...
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Valence Bond Theory02:42

Valence Bond Theory

10.8K
Coordination compounds and complexes exhibit different colors, geometries, and magnetic behavior, depending on the metal atom/ion and ligands from which they are composed. In an attempt to explain the bonding and structure of coordination complexes, Linus Pauling proposed the valence bond theory, or VBT, using the concepts of hybridization and the overlapping of the atomic orbitals. According to VBT, the central metal atom or ion (Lewis acid) hybridizes to provide empty orbitals of suitable...
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Complexation Equilibria: The Chelate Effect01:19

Complexation Equilibria: The Chelate Effect

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In complexation reactions, metal atoms or cations interact with ligands to form donor-acceptor adducts called metal complexes. Ligands that bind through one donor site are monodentate, ligands with two donor sites are bidentate, and those with more than two donor sites are polydentate ligands. For example, ethylene diamine is a bidentate ligand that binds through two nitrogen donor atoms, forming a five-membered ring. EDTA is a polydentate ligand that binds through four oxygen and two nitrogen...
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Formation of Complex Ions03:45

Formation of Complex Ions

25.3K
A type of Lewis acid-base chemistry involves the formation of a complex ion (or a coordination complex) comprising a central atom, typically a transition metal cation, surrounded by ions or molecules called ligands. These ligands can be neutral molecules like H2O or NH3, or ions such as CN− or OH−. Often, the ligands act as Lewis bases, donating a pair of electrons to the central atom. These types of Lewis acid-base reactions are examples of a broad subdiscipline called coordination...
25.3K
Crystal Field Theory - Octahedral Complexes02:58

Crystal Field Theory - Octahedral Complexes

29.9K
Crystal Field Theory
To explain the observed behavior of transition metal complexes (such as colors), a model involving electrostatic interactions between the electrons from the ligands and the electrons in the unhybridized d orbitals of the central metal atom has been developed. This electrostatic model is crystal field theory (CFT). It helps to understand, interpret, and predict the colors, magnetic behavior, and some structures of coordination compounds of transition metals.
CFT focuses on...
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Related Experiment Video

Updated: Dec 12, 2025

Structure and Coordination Determination of Peptide-metal Complexes Using 1D and 2D 1H NMR
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Structure and Coordination Determination of Peptide-metal Complexes Using 1D and 2D 1H NMR

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Nucleobase Pair-Metal Dimer/Dinuclear Metal Cation Interaction: A Theoretical Study.

Ruby Srivastava1

  • 1Bioinformatics, CSIR-Centre for Cellular and Molecular Biology, Hyderabad 500607, India.

ACS Omega
|August 11, 2020
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Coinage metal dimers and cations interact with nucleobase pairs, forming stable metallo-DNA. These interactions enable potential applications in fluorescent markers and logic gates.

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Quantifying the Binding Interactions Between CuII and Peptide Residues in the Presence and Absence of Chromophores
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Area of Science:

  • Computational chemistry
  • Biophysical chemistry
  • Materials science

Background:

  • Nucleobase pair-metal interactions are crucial for biological applications due to their symmetry and stability.
  • Coinage metals (Ag, Au, Cu) and their dimers/cations are investigated for their unique electronic properties.

Purpose of the Study:

  • To investigate the interactions between coinage metal dimers/cations (M2, M2^2+) and various nucleobase pairs.
  • To explore the formation of stable metallo-DNA sequences and potential applications.

Main Methods:

  • Density Functional Theory (DFT) and Time-Dependent DFT (TDDFT) for quantum chemical calculations.
  • Analysis of electronic structures using partial density of states.
  • Atom-in-molecules analysis to predict noncovalent interactions.

Main Results:

  • Significant metallophilic interactions were observed between metal atoms (M-M distances shorter than van der Waals radii).
  • Nucleobase-M2^2+ complexes exhibit greater stability than nucleobase-M2 complexes.
  • Dinuclear metal cation-coordinated bonds in AAST base pairs lead to more stable metallo-DNA sequences.

Conclusions:

  • Nucleobase-metal complexes show promise for advanced applications.
  • Nucleobase-Cu2 complexes and nucleobase-Ag2^2+/Au2^2+ complexes are suitable for fluorescent markers and logic gate applications.
  • The study highlights the potential of metallo-DNA for novel functional materials.