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Updated: Dec 12, 2025

Spontaneous Murine Model of Anaplastic Thyroid Cancer
Published on: February 3, 2023
[Current treatment strategies for papillary thyroid microcarcinoma]
1Klinik für Endokrine Chirurgie, Katholisches Klinikum Mainz, An der Goldgrube 11, 55129, Mainz, Deutschland. theresia.weber@marienhaus.de.
Abstract:
Surgical treatment of papillary thyroid microcarcinoma (PTMC) is evolving more and more into a controversial issue. As in Japan more than 50% of PTMCs are only observed, an increasing number of physicians in the western world are calling for active surveillance instead of lobectomy or total thyroidectomy. Unifocal carcinomas of older patients without extrathyroidal growth or lymph node involvement seem to be candidates for active surveillance. First estimations for a lifelong observation show that patients <30 years old will have a probability of tumor progression of more than 60%. A decision for surgery versus active surveillance has to weigh up all the arguments for and against, which have to be discussed and planned in detail together with the patient.
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