Related Experiment Video For ancient nevus
Updated: Dec 12, 2025
Author Spotlight: Genetically Engineered Mouse Models and Pathological Characterization of Neurofibromatosis Type 1 Associated Tumors
Published on: May 17, 2024
Proliferative nodule resembling angiomatoid Spitz tumor with degenerative atypia arising within a giant congenital
Taylor L Braunberger1, Madeline Adelman2, Tor A Shwayder1
1Department of Dermatology, Henry Ford Hospital, Detroit, Michigan, USA.
Abstract:
Proliferative nodules arising within congenital melanocytic nevi often present a diagnostic challenge given a close resemblance to melanoma. Several morphologic variants have been characterized. In difficult cases, ancillary molecular tests can be used to better exclude the possibility of malignant degeneration. Herein, we report a case of an unusual proliferative nodule with overlapping features of angiomatoid Spitz tumor and ancient melanocytic nevus, which demonstrated normal findings on both chromosomal microarray and a gene expression profiling assay.
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