Quality and capacity indicators for hospitalized pediatric oncology patients with critical illness: A modified delphi

Anita V Arias1,2, Marcela Garza2, Srinivas Murthy3

  • 1Division of Pediatric Critical Care, University of Tennessee Health Science Center, Memphis, TN, USA.

Cancer Medicine
|August 11, 2020
PubMed

Insights

Hospitalized pediatric hematology-oncology patients need quality indicators for critical care. The PROACTIVE tool identifies key indicators like designated PICU areas and available pediatric intensivists to improve care in resource-limited settings.

Area of Science:

  • Pediatric Critical Care
  • Oncology
  • Healthcare Quality Improvement

Background:

  • Hospitalized pediatric hematology-oncology (PHO) patients face high risks of critical illness, particularly in resource-limited environments.
  • Existing quality indicators for PHO critical care are lacking, hindering institutional improvement efforts.

Purpose of the Study:

  • To identify and develop quality indicators for assessing the capacity and quality of pediatric critical care services for PHO patients.
  • To create the PROACTIVE (PediatRic Oncology cApaCity assessment Tool for IntensiVe carE) tool.

Main Methods:

  • A literature review identified potential indicators across structure, performance, and outcomes.
  • An international focus group and a modified Delphi process involving 36 experts refined these indicators.
  • Indicators were ranked by relevance and actionability through expert surveys.

Main Results:

  • The PROACTIVE tool comprises 119 indicators across eight domains and 22 subdomains.
  • High median importance and expert agreement were achieved for the indicators.
  • Top indicators include: designated PICU area, availability of pediatric intensivists, PHO physician involvement, trained nursing staff, and timely PICU transfer.

Conclusions:

  • PROACTIVE is a consensus-based tool designed to evaluate pediatric onco-critical care quality, especially in resource-limited settings.
  • Future work will focus on validating PROACTIVE by linking indicators to clinical outcomes and implementing it to address service gaps.
Abstract

Related Concept Videos

Pharmacokinetics in Pediatric Patients: Drug Excretion01:26

Pharmacokinetics in Pediatric Patients: Drug Excretion

In pediatric medicine, understanding the renal function and drug elimination nuances is crucial for administering safe and effective treatments. Newborns, in particular, display markedly slower renal functions than adults, profoundly affecting how drugs are cleared from their bodies. This slower drug clearance requires clinicians to extend the dosing intervals for many medications to prevent drug accumulation and toxicity while ensuring therapeutic efficacy.One key area where these adjustments...
131
Acute Kidney Injury V: Interprofessional Care01:20

Acute Kidney Injury V: Interprofessional Care

Acute Kidney Injury (AKI) requires a collaborative healthcare approach to restore renal function and prevent complications. Essential management strategies involve monitoring fluid and electrolyte balance, adjusting medications, initiating dialysis when necessary, and providing nutritional support.Fluid and Electrolyte ManagementFluid Monitoring: Regularly monitoring body weight, central venous pressure, and urine output helps detect fluid imbalances early. Patient intake and output are...
179
Drug Dosing: Infants and Children01:29

Drug Dosing: Infants and Children

Pediatric patient dosages diverge from adults due to disparities in body surface area, total body water, and extracellular fluid per kilogram of body weight. The dosing regimen considers the variations in pharmacokinetics and pharmacology across distinct age groups, encompassing preterm newborns, infants, young children, older children, and adolescents. Calculation of pediatric patient doses is predicated on determining body surface area, which exhibits a superior correlation with the child's...
153
Cancer Survival Analysis01:21

Cancer Survival Analysis

Cancer survival analysis focuses on quantifying and interpreting the time from a key starting point, such as diagnosis or the initiation of treatment, to a specific endpoint, such as remission or death. This analysis provides critical insights into treatment effectiveness and factors that influence patient outcomes, helping to shape clinical decisions and guide prognostic evaluations. A cornerstone of oncology research, survival analysis tackles the challenges of skewed, non-normally...
567
Pharmacokinetics in Pediatric Patients: Drug Distribution01:17

Pharmacokinetics in Pediatric Patients: Drug Distribution

Drug distribution in the pediatric population exhibits unique challenges and considerations due to the physiological differences between children, particularly neonates and infants, and adults. A crucial aspect of pediatric pharmacology is understanding how these differences impact the pharmacokinetics of various drugs, necessitating age-specific dosing strategies to ensure efficacy and safety.Neonates and infants have a higher total body water content, ~75%–90% of their body weight,...
175
Nursing Ethical Principles II01:27

Nursing Ethical Principles II

Ethical principles are essential in guiding nurses to fulfill their responsibilities, focusing on the quality of nursing care and decision-making. These principles, including autonomy, beneficence, non-maleficence, justice, and fidelity, shape the ethical framework within healthcare settings.
Consider the following scenario, which illustrates how these principles are applied in the care of Mr. John, a fifty-year-old teacher diagnosed with metastatic liver cancer.
Initially, Mr. John's...
1.8K