Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Current thinking on spondarthritides.

J M Moll1

  • 1Sheffield Center for Rheumatic Disease, Nether Edge Hospital, United Kingdom.

Comprehensive Therapy
|January 1, 1988
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Cross-resistance between taxanes and new hormonal agents abiraterone and enzalutamide may affect drug sequence choices in metastatic castration-resistant prostate cancer.

European journal of cancer (Oxford, England : 1990)·2013
Same author

The place of psoriatic arthritis in the spondarthritides.

Bailliere's clinical rheumatology·1994
Same author

Criteria for ankylosing spondylitis: facts and fallacies.

British journal of rheumatology·1988
Same author

Seronegative arthropathies in the foot.

Bailliere's clinical rheumatology·1987
Same author

Proper poster presentation: a visual and verbal ABC.

British journal of rheumatology·1987
Same author

Pathogenic mechanism of B27 related seronegative polyarthritis: interplay between genetic and environmental factors.

Clinical and experimental rheumatology·1987
Same journal

Heparin-induced thrombocytopenia and thrombosis.

Comprehensive therapy·2011
Same journal

Antiplatelet therapy in cardiovascular disease.

Comprehensive therapy·2011
Same journal

Genetics of cardiovascular disease.

Comprehensive therapy·2011
Same journal

Septic renal vein thrombosis complicated by septic pulmonary embolism.

Comprehensive therapy·2011
Same journal

Gout and hyperuricemia.

Comprehensive therapy·2011
Same journal

Problems with computerized health records.

Comprehensive therapy·2011
See all related articles

This review covers spondarthritis, exploring HLA-B27

Area of Science:

  • Rheumatology and Immunology
  • Spondyloarthritis Pathogenesis and Diagnostics

Background:

  • Spondyloarthritis encompasses a group of inflammatory diseases.
  • Understanding the etiopathogenesis of spondarthritis is crucial for effective management.
  • Current diagnostic modalities and therapeutic strategies require ongoing evaluation.

Purpose of the Study:

  • To review current understanding of spondarthritis.
  • To discuss etiopathogenetic factors including HLA-B27 and bacterial infections.
  • To summarize diagnostic approaches and therapeutic options.

Main Methods:

  • Review of current literature on spondarthritis.
  • Discussion of genetic factors (HLA-B27 structure and distribution).
  • Exploration of infectious triggers.

Related Experiment Videos

  • Overview of diagnostic imaging techniques: infrared thermography, radionuclide scintigraphy, computerized tomography.
  • Analysis of current and emerging therapeutic interventions.

    • Main Results:

    • The role of HLA-B27 structure and population distribution in spondarthritis is considered.
    • Bacterial infection is highlighted as a potential factor in disease development.
    • Diagnostic imaging techniques offer varied insights into the disease process.
    • Treatment strategies include NSAIDs, exercise, surgery, and emerging use of sulfasalazine.

    Conclusions:

    • Current thinking on spondarthritis involves genetic predisposition (HLA-B27) and potential infectious triggers.
    • A combination of advanced imaging and established treatments, including newer agents like sulfasalazine, is key.
    • Further research into etiopathogenesis and therapeutic efficacy is warranted.