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Updated: Dec 12, 2025

Development and Functionalization of Electrolyte-Gated Graphene Field-Effect Transistor for Biomarker Detection
Published on: February 1, 2022
Graphene biosensors for bacterial and viral pathogens
Zixin Jiang1, Bo Feng1, Jin Xu1
1College of Environment and Resources, Xiangtan University, Xiangtan, 411105, Hunan Province, China.
Graphene biosensors offer a sensitive and stable method for detecting pathogens like viruses and bacteria. This review explores their development, mechanisms, and future potential for epidemic prevention.
Area of Science:
- Nanotechnology
- Biosensors
- Pathogen Detection
Background:
- Pathogen spread (e.g., COVID-19) threatens global health.
- Accurate pathogen monitoring is crucial for clinical, food, and environmental safety.
- Graphene's unique properties make it ideal for advanced biosensor construction.
Purpose of the Study:
- To review the development of graphene-based biosensors for pathogen detection.
- To elucidate the preparation methods and working mechanisms of these biosensors.
- To discuss current challenges and future perspectives in pathogen sensing.
Main Methods:
- Literature review of graphene biosensor development.
- Analysis of graphene material properties and their integration with biomolecules.
- Examination of working principles for pathogen detection.
Main Results:
- Graphene biosensors demonstrate enhanced stability and sensitivity for pathogen detection.
- The combination of graphene with specific biomolecules is a key strategy.
- Significant progress has been made in detecting bacterial and viral pathogens.
Conclusions:
- Graphene biosensors represent a promising technology for rapid and accurate pathogen identification.
- Further research can optimize these biosensors for improved epidemic prevention.
- Continued development is essential for advancing pathogen sensing technologies.
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