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A Scientific Journey with Ionophore-based Sensors
1Department of Inorganic and Analytical Chemistry, University of Geneva, Quai E.-Ansermet 30, CH-1211 Geneva 4, Switzerland;,
Chimia
|August 12, 2020
Summary
This review highlights the historical development and diverse applications of neutral ionophore-based sensors. These sensors have advanced analytical sciences, enabling applications in clinical diagnostics and environmental monitoring.
Area of Science:
- Electrochemistry
- Analytical Chemistry
- Sensor Technology
Background:
- The discovery of neutral ionophores by Wilhelm Simon revolutionized sensor development.
- Initial challenges in understanding ionophore function spurred further research.
Purpose of the Study:
- To trace the historical evolution of neutral ionophore-based sensors.
- To showcase the author's contributions and diverse applications in the field.
Main Methods:
- Review of historical milestones and key research contributions.
- Exploration of thermodynamic principles and non-equilibrium potentiometry.
- Discussion of advanced sensor designs and readout techniques.
Main Results:
- Demonstrated the significant impact of ionophore-based sensors on analytical sciences.
- Highlighted advancements from basic principles to complex applications.
- Showcased applications in clinical diagnostics, environmental sensing, and speciation analysis.
Conclusions:
- Neutral ionophore-based sensors have evolved significantly, offering versatile analytical capabilities.
- Continued innovation in sensor design and application broadens their utility.
- These sensors are crucial for in situ environmental monitoring and clinical diagnostics.

