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Updated: Dec 12, 2025

Quantifying Vibrio cholerae Colonization and Diarrhea in the Adult Zebrafish Model
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Zebrafish Models for Pathogenic Vibrios.

Dhrubajyoti Nag1, Dustin A Farr1, Madison G Walton1

  • 1Department of Biochemistry, Microbiology, and Immunology, Wayne State University School of Medicine, Detroit, Michigan, USA.

Journal of Bacteriology
|August 12, 2020
PubMed
Summary
This summary is machine-generated.

Zebrafish models are valuable for studying pathogenic Vibrio bacteria, which cause disease in aquatic animals and humans. This review summarizes current research utilizing zebrafish to understand Vibrio infections.

Keywords:
Vibrioanimal modelsbacterial pathogenesiszebrafish

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Area of Science:

  • Microbiology
  • Infectious Diseases
  • Aquatic Animal Health

Background:

  • The Vibrio genus comprises diverse bacteria, with some species being significant aquatic and human pathogens.
  • Zebrafish (Danio rerio) have become a crucial animal model for biological research, including infectious disease studies.

Purpose of the Study:

  • To review and summarize the application of zebrafish models in studying pathogenic Vibrio species.
  • To highlight the utility of zebrafish in understanding Vibrio-associated infections.

Main Methods:

  • Literature review of studies employing zebrafish to investigate pathogenic Vibrio species.
  • Analysis of research focusing on zebrafish as a model for Vibrio infections.

Main Results:

  • Zebrafish models have been successfully developed for various pathogenic Vibrio species.
  • The transparency of embryos and ease of genetic manipulation make zebrafish ideal for imaging and studying host-pathogen interactions.

Conclusions:

  • Zebrafish offer a powerful and relevant model system for studying Vibrio pathogenesis and developing control strategies.
  • Continued use of zebrafish models will advance our understanding of Vibrio diseases in aquatic environments and potentially human health.