Related Experiment Video
Updated: Dec 12, 2025

Visualization of Streptococcus pneumoniae within Cardiac Microlesions and Subsequent Cardiac Remodeling
Published on: April 7, 2015
Pericarditis as a cardiac manifestation of acute leptospirosis
1Institute for Infection Diseases and Infection Control, University Hospital Jena, Am Klinikum 1, 07747, Jena, Germany. maria.zechel@med.uni-jena.de.
Abstract:
Leptospirosis is an infectious disease with an increasing incidence worldwide. The clinical presentation is unspecific and ranges from an asymptomatic clinical course to an acute fulminant disease. The current case report describes a 32-year-old male patient who presented with ST segment elevation in the electrocardiogram about 14 days after cross-country running. Pericarditis was diagnosed and linked to an acute leptospirosis that was serologically confirmed.
Insights
Leptospirosis, an infectious disease, can cause heart inflammation like pericarditis. This case report highlights a runner diagnosed with acute leptospirosis after experiencing cardiac symptoms.
Area of Science:
- Cardiology
- Infectious Diseases
- Public Health
Background:
- Leptospirosis is a globally increasing zoonotic infection with diverse clinical manifestations.
- Early diagnosis and treatment are crucial for managing leptospirosis complications.
- Unspecific symptoms can delay diagnosis, necessitating a broad differential diagnosis.
Observation:
- A 32-year-old male presented with ST segment elevation on electrocardiogram.
- Symptoms appeared approximately 14 days after participating in cross-country running.
- Initial presentation mimicked acute cardiac events.
Findings:
- The patient was diagnosed with pericarditis.
- Serological tests confirmed an acute leptospirosis infection.
- The cardiac condition was directly linked to leptospirosis.
Implications:
- This case underscores the importance of considering infectious etiologies, such as leptospirosis, in patients with unexplained cardiac symptoms.
- Clinicians should maintain a high index of suspicion for leptospirosis in individuals with relevant exposure history, including outdoor activities.
- Prompt recognition and management of leptospirosis can prevent severe complications and improve patient outcomes.
Related Concept Videos
Pericarditis II: Clinical Features and Diagnostic Tests
Pericarditis I: Introduction
Myocarditis II: Clinical Features and Diagnostic Tests
Rheumatic Heart Disease I: Introduction
Endocarditis II: Clinical Features of Infective Endocarditis
Rheumatic Heart Disease II: Clinical Manifestations and Diagnostic Studies

