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Updated: Dec 12, 2025

Using a Murine Model of Psychosocial Stress in Pregnancy as a Translationally Relevant Paradigm for Psychiatric Disorders in Mothers and Infants
Published on: June 13, 2021
Covid-19 pandemic and pregnancy.
Satoshi Hayakawa1, Shihoko Komine-Aizawa1, Gil G Mor2
1Division of Microbiology, Department of Pathology and Microbiology, Nihon University School of Medicine, Tokyo, Japan.
Pregnant women with COVID-19 show no increased risk of miscarriage or preterm birth. However, standard precautions are crucial as SARS-CoV-2 can transmit to pregnant individuals.
Area of Science:
- Virology
- Obstetrics
- Public Health
Background:
- The emergence of COVID-19 (Coronavirus Disease 2019) caused by SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus 2) in late 2019 prompted global concern.
- SARS-CoV-2 shares characteristics with other beta-coronaviruses like SARS and MERS.
- The impact of SARS-CoV-2 on pregnant women and fetuses became a significant focus for obstetricians.
Purpose of the Study:
- To evaluate the current understanding of COVID-19's impact on pregnant women and fetal outcomes.
- To clarify the risks associated with SARS-CoV-2 infection during pregnancy.
Main Methods:
- Review of existing literature and clinical observations regarding COVID-19 in pregnancy.
- Analysis of reported outcomes including miscarriage, stillbirth, preterm labor, and teratogenicity.
Main Results:
- Current data suggests COVID-19 is not significantly more severe in pregnant women compared to the general population.
- COVID-19 infection during pregnancy has not been shown to increase rates of miscarriage, stillbirth, or preterm labor.
- Teratogenic effects of SARS-CoV-2 have not been established.
Conclusions:
- While direct adverse fetal outcomes appear uncommon, pregnant women remain susceptible to SARS-CoV-2 infection.
- Transmission of SARS-CoV-2 to pregnant women by asymptomatic carriers is possible.
- Adherence to standard infection control precautions in clinical and laboratory settings is essential for healthcare personnel.
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