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Type 4 hypersensitivity development in a case due to mifamurtide

Meral Şimşek1, Erman Ataş2, Emin Ümit Bağrıaçık3

  • 1Department of Pediatrics, Gülhane Faculty of Medicine, Ankara, Turkey.

The Turkish Journal of Pediatrics
|August 12, 2020
PubMed
Summary

Mifamurtide, an immunotherapy for osteosarcoma, can cause delayed hypersensitivity reactions like pleural and pericardial effusion. Treatment with colchicine resolved these effusions, suggesting an immune-mediated mechanism.

Keywords:
childhypersensitivitymifamurtideosteosarcomapericardial effusionpleural effusion

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