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Updated: Dec 12, 2025

Author Spotlight: Advancements in In Vivo and Ex Vivo Retinal Imaging for Improved Glaucoma Diagnosis and Treatment
Published on: June 30, 2023
[Choroid and optical defocus]
E P Tarutta1, S V Milash1, G A Markosyan1
1Helmholtz National Medical Research Center of Eye Diseases, Moscow, Russia.
Abstract:
The review summarizes experimental and clinical data attesting to the important role the choroid plays in the development of refraction through optically oriented thickness changes and the release of growth factors. Because of its unique anatomical position, the choroid can influence the transmission of a cascade of chemical signals from the retina to the sclera and thereby affect the growth of the eye. Understanding the relationship between the optical defocus and the response of the choroid to it will help uncover the fundamental mechanisms for controlling eye growth and develop new strategies for preventing the progression of myopia.
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