Related Experiment Video
Updated: Dec 12, 2025
08:03
Isolation of Salivary Epithelial Cells from Human Salivary Glands for In Vitro Growth as Salispheres or Monolayers
Published on: July 15, 2019
9.5K
[Salivary gland carcinoma]
G Lassche1, A C H van Engen-van Grunsven2, J Honings3
1Radboudumc, afd. Medische Oncologie, Nijmegen.
Nederlands Tijdschrift Voor Geneeskunde
|August 12, 2020
Summary
Salivary gland cancer, a rare head and neck malignancy, presents diverse subtypes and challenges in diagnosis and treatment. Case studies highlight recent therapeutic advancements for these complex cancers.
Area of Science:
- Oncology
- Head and Neck Surgery
Background:
- Salivary gland cancer is a rare malignancy originating in the head and neck.
- It exhibits significant clinical heterogeneity with 22 distinct subtypes.
- Variations in symptoms, treatment, and prognosis complicate diagnosis and management.
Observation:
- Two patient cases illustrate the complexities of salivary gland cancer.
- A 62-year-old man with salivary duct carcinoma was studied.
- A 56-year-old man with adenoid cystic carcinoma was analyzed.
Findings:
- The heterogeneity of salivary gland cancer subtypes leads to diagnostic and therapeutic challenges.
- Advances in treatment strategies are being made for these rare cancers.
- Specific case examples demonstrate progress in managing salivary duct carcinoma and adenoid cystic carcinoma.
Implications:
- Improved diagnostic accuracy is crucial for effective salivary gland cancer management.
- Tailored treatment approaches based on subtype are essential.
- Ongoing research and case studies are vital for advancing the care of patients with salivary gland cancer.
More Related Videos
Related Concept Videos
01:23Salivary Glands and Saliva
1.9K
The salivary glands, of which there are three pairs known as the parotid, submandibular, and sublingual glands, play a crucial role in maintaining oral health and initiating the digestive process. Positioned near the ears, beneath the masseter muscle, the parotid glands secrete saliva into the oral cavity through the parotid duct of Stensen. Meanwhile, the submandibular glands, located on the floor of the mouth, secrete saliva through channels named submandibular ducts. The sublingual glands,...
1.9K
01:03Rous Sarcoma Virus (RSV) and Cancer
5.9K
Rous Sarcoma virus or RSV was discovered by F. Peyton Rous in the year 1911 as a filterable transmissible agent that could cause tumors in chickens. He won a Nobel Prize for this discovery in 1966. His experiments clearly demonstrated that some cancers could be caused by infectious agents and led to the discovery of many more cancer-causing viruses in animals as well as humans.
RSV is a retrovirus that contains two copies of a plus-strand RNA genome. Its genome consists of four main open...
RSV is a retrovirus that contains two copies of a plus-strand RNA genome. Its genome consists of four main open...
5.9K
01:13Exocrine Glands: Types of Secretions
3.5K
Exocrine glands produce and release a variety of glandular products. Exocrine glands can be classified into serous, mucous, or mixed types based on their secretory products.
Serous glands produce watery secretions rich in digestive enzymes and proteins. The constituent cells of the serous gland have centrally located nuclei and eosinophilic secretory granules in the cytoplasm. The parotid gland is an example of a serous gland. It secretes saliva, which contains enzymes, such as lipases and...
Serous glands produce watery secretions rich in digestive enzymes and proteins. The constituent cells of the serous gland have centrally located nuclei and eosinophilic secretory granules in the cytoplasm. The parotid gland is an example of a serous gland. It secretes saliva, which contains enzymes, such as lipases and...
3.5K
01:20Classification of Epithelial Tissues: Glandular Epithelium
11.4K
The glandular epithelium is made of one or more epithelial cells modified to synthesize and secrete chemical substances. Glandular epithelia can be classified based on cell number. Unicellular glands have individual secretory cells scattered across the epithelial monolayer. In contrast, multicellular glands consist of a hollow tubular duct attached to the cluster of secretory cells located in the deep pockets.
Multicellular glands are formed during early development when epithelial budding...
Multicellular glands are formed during early development when epithelial budding...
11.4K
01:29Exocrine Glands: Unicellular and Multicellular Glands
30.4K
Exocrine glands are classified as unicellular and multicellular. The unicellular glands are scattered single cells, such as goblet cells, found in the mucous membranes of the small and large intestines. On the other hand, multicellular exocrine glands develop as secretory sheets, like the internal lining of the abdomen or chest. Such secretory sheets release their secretions directly into the lumen of these organs. In addition, some multicellular glands have deep-seated secretory units to...
30.4K