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Updated: Dec 12, 2025

Implantation of Total Artificial Heart in Congenital Heart Disease
Published on: July 18, 2014
New developments in adult congenital heart disease
B J Bouma1, G T Sieswerda2, M C Post3
1Department of Cardiology, Amsterdam UMC, University of Amsterdam, Heart Center, Amsterdam Cardiovascular Sciences, Amsterdam, The Netherlands. b.j.bouma@amsterdamumc.nl.
Insights
Advances in treating congenital heart disease (CHD) have increased survival, but late complications remain a challenge. Continuous innovation in diagnostics and care is crucial for improving outcomes in adults with CHD.
Area of Science:
- Cardiology
- Pediatric Cardiology
- Adult Congenital Heart Disease
Background:
- Congenital heart disease (CHD) affects 0.8% of live births, with survival rates exceeding 95% into adulthood due to improved treatments.
- Adult survivors of CHD face significant risks of late complications, including heart failure, pulmonary hypertension, arrhythmias, aneurysms, and endocarditis, impacting morbidity and mortality.
- Recent innovations have transformed the management landscape for adult CHD patients.
Purpose of the Study:
- To review recent advancements in the diagnosis and treatment of adult congenital heart disease.
- To highlight the evolving challenges and improved outcomes for adult CHD patients.
- To emphasize the importance of specialized care, multidisciplinary collaboration, and ongoing research in managing adult CHD.
Main Methods:
- Review of innovations in diagnostic tools, including MRI, biomarkers, e-health, and 3D visualization.
- Description of the shift towards specialized centers with multidisciplinary consultations for diagnosis and intervention.
- Overview of refined surgical and percutaneous interventions and evolving research methodologies from case series to global networks.
Main Results:
- Significant improvements in diagnostic accuracy and visualization techniques for adult CHD.
- Enhanced care models through specialized centers and multidisciplinary teams.
- Refined interventional strategies leading to reduced burden of congenital malformations.
Conclusions:
- Despite improved survival, adults with CHD continue to face substantial risks of early mortality and morbidity.
- Global collaboration, continuous education, and innovation in diagnostic and therapeutic approaches are essential for improving the long-term outlook for adult CHD patients.
- The field of adult CHD is rapidly evolving, necessitating ongoing adaptation and advancement in care strategies.
Abstract:
Congenital heart disease (CHD) affects 0.8% of live births and over the past decades technical improvements and large-scale repair has led to increased survival into adulthood of over 95% of the new-born. A new group of patients, those who survived their congenital heart defect, has emerged but late complications including heart failure, pulmonary hypertension (PH), arrhythmias, aneurysms and endocarditis appeared numerous, with a huge impact on mortality and morbidity. However, innovations over the past years have changed the landscape of adult CHD dramatically. In the diagnostic process important improvements have been made in the use of MRI, biomarkers, e‑health concepts and 3D visualisation of anatomy. Care is now concentrated in specialised centres, with a continuous emphasis on education and the introduction of weekly multidisciplinary consultations on diagnosis and intervention. Surgery and percutaneous intervention have been refined and new concepts applied, further reducing the burden of the congenital malformations. Research has matured from case series to global networks. Currently, adults with CHD are still facing high risks of early mortality and morbidity. By global collaboration and continuous education and development and innovation of our diagnostic and therapeutic arsenal, we will improve the perspectives of these young patients.
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