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The Mexican Cognitive Aging Ancillary Study (Mex-Cog): Study Design and Methods.
Silvia Mejia-Arango1, Rene Nevarez2, Alejandra Michaels-Obregon3
1Department of Population Studies, El Colegio de la Frontera Norte, Tijuana, Baja California, Mexico.
Archives of Gerontology and Geriatrics
|August 12, 2020
Summary
The Cognitive Aging Ancillary Study in Mexico (Mex-Cog) offers detailed cognitive data on older adults. This research enhances understanding of cognitive aging and dementia trends, with data accessible globally.
Area of Science:
- Gerontology
- Neuroscience
- Epidemiology
Background:
- The Mexican Health and Aging Study (MHAS) is an ongoing longitudinal study.
- The Cognitive Aging Ancillary Study in Mexico (Mex-Cog) is a subsample of MHAS participants.
- Mex-Cog aligns with the Harmonized Cognitive Assessment Protocol (HCAP) for international dementia research.
Purpose of the Study:
- To conduct in-depth cognitive assessments in older Mexican adults.
- To facilitate cross-national comparisons of dementia prevalence and trends.
- To harmonize cognitive data with global studies for broader analysis.
Main Methods:
- Utilized a cognitive assessment instrument and an informant questionnaire.
- Selected and adapted cognitive measures for reliability and comparability.
- Employed the 10/66 Dementia Study informant questionnaire for Mexico.
Main Results:
- 2,265 participants aged 55-104 years were included, with a 70% response rate.
- Validity analyses confirmed content adequacy, data integrity, and high reliability.
- Internal structure analyses supported the robustness of the cognitive measures.
Conclusions:
- Mex-Cog provides rich cognitive data linked to MHAS longitudinal information.
- This linkage expands research on cognitive impairment and dementia in Mexican adults.
- Harmonized data enables global cross-national cognition studies, with data publicly available.
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