Related Experiment Video
Updated: Dec 12, 2025
06:39
Live Imaging of Dorsal Root Axons after Rhizotomy
Published on: September 1, 2011
14.1K
An uncommon type of segmental root development after revitalization
1Department of Pediatric Dentistry, Peking University School and Hospital of Stomatology, Beijing, China.
International Endodontic Journal
|August 12, 2020
Summary
Segmental root development, an uncommon outcome of endodontic revitalization, occurs when the apical root segment detaches and develops separately. This phenomenon, seen after trauma or inflammation, impacts root growth potential.
Area of Science:
- Endodontics
- Regenerative dentistry
- Dental traumatology
Background:
- Endodontic revitalization aims to promote continued root development in immature teeth.
- Segmental root development is an uncommon complication observed post-revitalization.
Observation:
- Four cases of immature teeth with extensive periapical lesions (trauma or dens evaginatus fracture) underwent revitalization.
- An unusual segmental root development was noted, where the apical root segment detached and developed independently.
Findings:
- The detached apical segments showed normal root tip morphology and structure.
- Main root body development ceased in all cases, but teeth remained functional and asymptomatic.
- Positive responses to electrical pulp tests were observed in two cases during follow-up.
Implications:
- Severe trauma or periapical lesions can displace Hertwig's epithelial root sheath and apical papilla, leading to segmental root development.
- This condition precludes normal root maturation; clinicians must consider this possibility in cases of severe dental trauma.
- Gentle revitalization techniques are crucial to protect apical structures and prevent iatrogenic abnormal root development.
Related Concept Videos
03:02Primary and Secondary Growth in Roots and Shoots
59.6K
Vascular plants, which account for over 90% of the Earth’s vegetation, all undergo primary growth—which lengthens roots and shoots. Many land plants, notably woody plants, also undergo secondary growth—which thickens roots and shoots.
59.6K
01:19Overview of Regeneration and Repair
4.9K
Regeneration and repair processes are critical in healing damages caused by injury, disease, and aging. In regeneration, the damaged tissue is entirely replaced with new growth that restores the original architecture and function. In contrast, tissue repair usually results in a fixed tissue architecture involving scar formation. Scars generally do not reestablish tissue function and may also exhibit structural abnormalities at the injury site.
Regeneration
All animals have varying degrees of...
Regeneration
All animals have varying degrees of...
4.9K
01:23Renewal of Intestinal Stem Cells
3.0K
The intestinal epithelial lining rapidly renews every 4 to 5 days. The renewal is facilitated by intestinal stem cells (ISCs) located at the base of the crypt– a gland located at the bottom of each villus. ISCs divide asymmetrically to form new stem cells and progenitor daughter cells. The daughter cells are called transit-amplifying (TA) cells which move upwards along the crypt and either differentiate into absorptive cells– the enterocytes or secretory cells– including the...
3.0K
01:33Whole Body Regeneration
3.9K
Regeneration is the process of restoring injured or lost tissues, organs, or body parts. While simpler organisms generally show greater ability to regenerate their whole body, few complex animals show similarly exceptional regeneration. For example, planarian flatworms have a unique regenerative potential making them a popular study organism among biologists to understand the mechanisms of whole body regeneration. Other organisms, such as hydra, also show extreme regeneration potential;...
3.9K
01:23Tissue Renewal without Stem Cells
2.0K
After cellular or tissue damage, the resident stem cells present in the human body can locally repair and regenerate the damaged tissue or organ. However, even though some tissues do not have stem cells, they can repair and regenerate with the help of pre-existing cells. For example, beta cells of the pancreas and hepatocytes of the liver can divide to renew and regenerate the tissue. Here, both cell division and cell death are well regulated by homeostasis.
However, failure of such a system...
However, failure of such a system...
2.0K
01:15Neurogenesis and Regeneration of Nervous Tissue
1.4K
In the CNS, neurogenesis, the birth of new neurons from stem cells, is limited to the hippocampus in adults. In other regions of the brain and spinal cord, neurogenesis is almost non-existent due to inhibitory influences from neuroglia, especially oligodendrocytes, and the absence of growth-stimulating cues. The myelin produced by oligodendrocytes in the CNS inhibits neuronal regeneration. Furthermore, astrocytes proliferate rapidly after neuronal damage, forming scar tissue that physically...
1.4K