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Updated: Dec 12, 2025

Assessment of Cardiac Morphological and Functional Changes in Mouse Model of Transverse Aortic Constriction by Echocardiographic Imaging
Published on: June 21, 2016
[Saw tooth cardiomyopathy: How to better diagnose?]
M T Bailly1, T Vasile2, E Berthelot1
1Service de cardiologie, hôpital Bicêtre, AP-HP, France.
Sawtooth cardiomyopathy, a rare myocardial dysplasia often mistaken for left ventricular non-compaction, presents diagnostic challenges. This study clarifies its MRI and echocardiography criteria, highlighting its underdiagnosis and prognostic importance.
Area of Science:
- Cardiology
- Medical Imaging
- Pathology
Background:
- Cardiac Magnetic Resonance (CMR) imaging is increasingly utilized.
- Rare forms of myocardial dysplasia, termed "sawtooth cardiomyopathy" or "tiger heart," are infrequently reported.
- The pathological characteristics and prognostic implications of these conditions are not well-understood.
Observation:
- A case of sawtooth cardiomyopathy in a patient experiencing a transient ischemic attack is presented.
- This condition is often misdiagnosed or equated with left ventricular non-compaction.
- Diagnostic criteria using MRI and echocardiography require further elucidation.
Findings:
- Sawtooth cardiomyopathy is characterized by specific patterns on cardiac MRI and echocardiography.
- Establishing clear diagnostic criteria is crucial for accurate identification.
- The association with transient ischemic attacks suggests potential cardiovascular risks.
Implications:
- Sawtooth cardiomyopathy may be significantly underdiagnosed in clinical practice.
- Increased awareness and standardized diagnostic criteria are needed.
- Further research into the prognostic implications of this condition is warranted.
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