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Updated: Dec 12, 2025

Endoscopic Vacuum Therapy for the Treatment of Anastomotic Leakage after Total Gastrectomy with Esophagojejunostomy
Published on: August 22, 2025
Negative Pressure Therapy for Management of High Output Duodenal Fistula
Omar S El-Ghazzawy1, Jordan Shively2, Christian Massier1
1General Surgery, Cleveland Clinic South Pointe Hospital, Warrensville Heights, USA.
Abstract:
This case study describes a patient with duodenal perforation caused by foreign body ingestion who postoperatively developed high output duodenal fistula and intra-abdominal sepsis. The management of this complication included the unique application of negative pressure wound vacuum therapy via retroperitoneal drains. This assisted the closure of the duodenal fistula, prevented surgical reintervention, helped control intra-abdominal sepsis, and simplified local wound care. Application of closed incision negative pressure therapy to the retroperitoneal space via surgical drains is a technically easy and well-tolerated modality that accelerates duodenal fistula closure.
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