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Antiviral Activity of Nanomaterials against Coronaviruses

Wali Muhammad1, Zihe Zhai1, Changyou Gao1

  • 1W. Muhammad, Z. Zhai, Prof. C. Gao, MOE Key Laboratory of Macromolecular Synthesis and Functionalization, Department of Polymer Science and Engineering, Zhejiang University, Hangzhou, 310027, China.

Macromolecular Bioscience
|August 13, 2020
PubMed

Insights

Nanotechnology offers promising solutions for combating coronaviruses (CoVs), including SARS-CoV-2. This review explores nanomaterials

Area of Science:

  • Nanomedicine
  • Microbiology
  • Virology

Background:

  • Coronaviruses (CoVs), particularly SARS-CoV-2, pose significant global public health threats, causing severe pneumonia and lacking vaccines.
  • The emergence of novel CoV strains and their extensive infectivity in humans and animals present a critical challenge for researchers.
  • Current antiviral drug development and vaccine creation for CoVs remain significant hurdles for the scientific community.

Purpose of the Study:

  • To review existing and recent research on the application of nanomaterials against coronaviruses.
  • To explore the potential of nanotechnology as a platform for developing novel therapeutic strategies against CoVs.
  • To identify future research directions for utilizing nanomaterials in combating coronavirus infections.

Main Methods:

  • Comprehensive literature review of studies investigating nanomaterial-coronavirus interactions.
  • Analysis of the unique physicochemical properties of nanomaterials relevant to antimicrobial applications.
  • Synthesis of information on previous and current research findings.

Main Results:

  • Nanomaterials exhibit unique properties that enable interaction with microorganisms, suggesting potential therapeutic applications.
  • Evidence suggests that nanomaterial-antimicrobial interactions can be a viable strategy for treating viral infections.
  • The review highlights the growing body of research supporting nanotechnology's role in combating viral pathogens.

Conclusions:

  • Nanotechnology presents a promising multidisciplinary approach to address the challenges posed by coronavirus infections.
  • Further research into nanomaterial-based strategies is crucial for developing effective treatments and countermeasures against CoVs.
  • The unique properties of nanomaterials offer novel avenues for future therapeutic interventions against emerging viral threats.
Keywords:
COVID-19CoVMERSSARSnanoparticlesnanotechnology

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