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Updated: Dec 12, 2025

Combining Behavior and EEG to Study the Effects of Mindfulness Meditation on Episodic Memory
Published on: May 11, 2020
Comparing focused attention meditation to meditation with mobile neurofeedback for persistent symptoms after
Ginger Polich1, Sarah Gray1, Duc Tran2
1Department of Physical Medicine and Rehabilitation, Spaulding Rehabilitation Hospital/Harvard Medical School , Charlestown, MA, USA.
Primary Objective:
This study evaluated whether a meditation practice incorporating mobile neurofeedback (mNF) offers any advantage over a more traditional form of focused attention (FA) meditation in managing persistent symptoms after traumatic brain injury (TBI) (clinicaltrials.gov NCT02615535).
Research Design:
Pilot randomized clinical trial, exploring feasibility of mNF in TBI.
Methods And Procedures:
Participants included adults with chronic mood and/or cognitive complaints following mild-moderate TBI. Subjects practiced either FA (n = 10) or mNF (n = 10) meditation 12 minutes daily for 6 weeks. Pre-post intervention difference on the Neurobehavioral Symptom Inventory (NSI) was the primary outcome variable. Secondary outcomes included the Beck Anxiety Inventory (BAI), Beck Depression Inventory-II (BDI-II), amongst other scales and neurocognitive tests.
Main Outcomes And Results:
No significant pre-post between-group differences were found on the NSI (p = .838) nor other assessments. In an exploratory analysis combining FA and mNF data, meditation was associated with significant improvements on the NSI (p = .04), BAI (p = .012) and BDI (p = .037).
Conclusions:
Meditating with neurofeedback does not appear to provide an advantage over meditating on one's own for chronic post-TBI symptoms. Further research on home-based meditation following TBI, whether self-directed or technologically facilitated, is warranted.

