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Enzyme catalysis powered micro/nanomotors for biomedical applications
Motilal Mathesh1, Jiawei Sun, Daniela A Wilson
1Institute of Molecules and Materials, Radboud University, Heyendaalseweg 135, 6525 AJ, Nijmegen, The Netherlands. d.wilson@science.ru.nl.
Journal of Materials Chemistry. B
|August 14, 2020
Summary
Enzyme powered motors offer autonomous motion for targeted biomedical delivery using natural fuels. This review details their design, fabrication, and propulsion for advanced medical technologies.
Area of Science:
- Biomedical Engineering
- Nanotechnology
- Biophysics
Background:
- Artificial systems are increasingly developed for autonomous motion with biomedical applications.
- Enzyme powered motors are promising for active and targeted delivery systems.
- These motors utilize physiological fuels for catalytic reactions, enabling in vivo motion.
Purpose of the Study:
- To review the design and fabrication of enzyme powered motors.
- To discuss propulsion mechanisms using biologically relevant fuels.
- To highlight recent advances and design considerations for biomedical applications.
Main Methods:
- Review of existing literature on enzyme powered motors.
- Analysis of fabrication techniques and propulsion strategies.
- Discussion of parameters for in vivo application.
Main Results:
- Enzyme powered motors can be designed and fabricated using various strategies.
- Propulsion mechanisms effectively utilize endogenous fuels for motion.
- Recent advances show significant potential for targeted biomedical delivery.
Conclusions:
- Enzyme powered motors represent a key technology for next-generation biomedical applications.
- Further research into design parameters will enhance their in vivo performance.
- This review provides insights for developing advanced enzyme powered motor systems.
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