Related Experiment Video

Updated: Dec 12, 2025

Characterization of Sickling During Controlled Automated Deoxygenation with Oxygen Gradient Ektacytometry
08:23

Characterization of Sickling During Controlled Automated Deoxygenation with Oxygen Gradient Ektacytometry

Published on: November 5, 2019

10.2K

BEHAVIORAL CHARACTERISTICS OF CHILDREN WITH SICKLE CELL DISEASE

Fellipe Bondança Pereira1, Glaura César Pedroso1, Rosa Miranda Resegue1

  • 1Universidade Federal de São Paulo, São Paulo, SP, Brazil.

Revista Paulista De Pediatria : Orgao Oficial Da Sociedade De Pediatria De Sao Paulo
|August 14, 2020
PubMed

Insights

Behavioral issues are common in children with sickle cell disease (SCD). Lower socioeconomic status is linked to increased behavioral impacts in these children.

Area of Science:

  • Pediatric Hematology
  • Child Psychology
  • Public Health

Background:

  • Sickle cell disease (SCD) is a genetic blood disorder impacting children's health.
  • Behavioral and sociodemographic factors in pediatric SCD require further investigation.

Purpose of the Study:

  • To assess sociodemographic and clinical characteristics of children with SCD.
  • To evaluate behavioral patterns in children diagnosed with SCD using the Strengths and Difficulties Questionnaire (SDQ).

Main Methods:

  • Interviews with parents of 45 children (ages 4-10) with SCD.
  • Collected clinical data from medical records, excluding specific treatments or conditions.
  • Administered the SDQ to assess behavioral difficulties.

Main Results:

  • 88.9% of children showed clinical impact on the SDQ, particularly in the emotional subscale (68.9%).
  • Children from lower socioeconomic classes (C2 and D) experienced significantly more behavioral impacts (61.3%) compared to higher classes (B2 and C1, 21.4%).
  • Higher prevalence of behavioral impacts was observed in children whose family head had less formal education.

Conclusions:

  • Behavioral impacts are highly prevalent in children with sickle cell disease.
  • Socioeconomic status significantly influences the manifestation of behavioral difficulties in pediatric SCD patients.
Abstract

More Related Videos

A Precision Medicine Tool for Measurement and Monitoring of Hemoglobin S in Sickle Cell Disease Patients Receiving Transfusion Therapy07:24

A Precision Medicine Tool for Measurement and Monitoring of Hemoglobin S in Sickle Cell Disease Patients Receiving Transfusion Therapy

1.8K
Continuous Manual Exchange Transfusion for Patients with Sickle Cell Disease: An Efficient Method to Avoid Iron Overload05:23

Continuous Manual Exchange Transfusion for Patients with Sickle Cell Disease: An Efficient Method to Avoid Iron Overload

Published on: March 14, 2017

20.1K

Related Concept Videos

Multiple Allele Traits01:49

Multiple Allele Traits

The Concept of Multiple Allelism
37.6K
Conduct Disorder01:28

Conduct Disorder

Conduct disorder is a complex mental health diagnosis characterized by a repetitive and persistent pattern of behavior that violates societal norms, the rights of others, or age-appropriate rules. The diagnostic criteria for conduct disorder require the presence of at least three problematic behaviors within the past 12 months, with at least one occurring in the past six months. These behaviors are grouped into four categories: aggression toward people and animals; destruction of property;...
347
Classification of Illness01:17

Classification of Illness

The meaning of illness is individualized to each person who experiences an alteration in health. In contrast, disease is a medical term indicating a pathological change in the structure and function of the body or mind. It is a condition that has specific symptoms and boundaries.
An illness is a response to a disease in which the person's level of functioning is changed compared with a previous level. The general classification of illness includes acute and chronic.
Acute illness is severe...
8.4K
Oppositional Defiant Disorder01:30

Oppositional Defiant Disorder

A persistent pattern of angry or irritable mood, defiant behavior, or vindictiveness characterizes Oppositional Defiant Disorder (ODD). Symptoms must occur over at least six months, involve interactions with individuals beyond siblings, and meet specific diagnostic criteria to be clinically significant. The disorder affects emotional regulation, social interactions, and behavior, often manifesting early in life and influencing long-term development and functioning.
Diagnostic Criteria and...
420
Disorders of Erythrocytes01:27

Disorders of Erythrocytes

Disorders of erythrocytes, or red blood cells (RBCs), include a range of conditions affecting their number, shape, or function.
Erythrocyte disorders can be broadly categorized into two main types: anemic and polycythemic conditions.
A low oxygen-carrying capacity of the blood due to the loss, lower production, or destruction of erythrocytes is termed anemia. Hemorrhagic anemia, for example, occurs when bleeding from an external wound or internal ulcer reduces erythrocyte counts.
On the other...
1.9K
Socioemotional Development during Infancy01:30

Socioemotional Development during Infancy

Socio-emotional development in infancy is primarily shaped by early emotional responses and social connections, with temperament playing a central role. Temperament refers to the consistent patterns in an individual's emotional and behavioral responses, observable even in infancy. By examining temperament, researchers can better understand an infant's unique ways of interacting with the world, influencing subsequent personality and socio-emotional growth.
Primary Temperament Types
313