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An HIV-infected patient with coronavirus disease 2019 has a favourable prognosis: a case report
Chong Tian1, Lei Tang1, Jiahong Wu2
1Department of Medical Imaging, Guizhou Provincial People's Hospital, Guiyang, China.
Insights
People with human immunodeficiency virus (HIV) on antiretroviral therapy (ART) may experience favorable outcomes when infected with coronavirus disease 2019 (COVID-19). Regular ART appears crucial for managing COVID-19 in HIV patients.
Area of Science:
- Infectious Diseases
- Immunology
- Virology
Background:
- Coronavirus disease 2019 (COVID-19) pandemic presents unique challenges for immunocompromised populations.
- The impact of COVID-19 on individuals with human immunodeficiency virus (HIV) is debated, with differing views on risk and prognosis.
- Some research suggests HIV antiretroviral therapy (ART) may offer protection against SARS-CoV-2, while others cite immunosuppression as an increased risk factor.
Observation:
- A case study of a 24-year-old male with HIV, undergoing regular ART, who contracted COVID-19 is presented.
- The patient experienced only mild, short-term fever and no other significant symptoms or complications during his COVID-19 illness.
Findings:
- Despite living with HIV, the patient demonstrated a favorable prognosis following COVID-19 infection.
- Lung lesions observed on chest CT scans resolved rapidly, and the patient was cured and discharged within 9 days of standard treatment.
Implications:
- This case underscores the critical role of consistent antiretroviral therapy (ART) in managing HIV.
- Regular ART adherence in individuals with HIV may mitigate the severity of coronavirus disease 2019 (COVID-19) and improve patient outcomes.
Abstract:
The coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has spread rapidly, which now has turned into a pandemic. The new emerging infectious disease has raised many challenges and uncertainties regarding disease management and prognosis in immunocompromised patient populations. The risk of COVID-19 among people living with human immunodeficiency virus (HIV) has different opinions. Some scholars speculated that patients with HIV may be at decreased risk for complications of COVID-19 because HIV antiretroviral medications may have activity against coronaviruses such as SARS-CoV-2. But others have the opposite because of the immunosuppression for HIV patients. Here we reported a case of HIV-infected patient confirmed with COVID-19 and had a favourable prognosis. The patient was a 24-year-old male who was diagnosed with HIV infection 2 years ago and then followed a regular antiretroviral therapy (ART). After infected with COVID-19, the patient had no other clinical symptoms and laboratory abnormalities throughout the course of the disease except presented with fever for a short-term (2 days), and no secondary infection or exacerbation occurred after admission in hospital. Follow-up chest CT showed that the lung lesions disappeared within a short period of time. After standard treatment by 9 days, the patient was cured and discharged. This report highlights the importance of ART for HIV-infected persons, and with regular ART for HIV patients may reduce adverse consequences after infection with COVID-19.
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