Related Experiment Video
Updated: Dec 12, 2025
Development and Implementation of a Multi-Disciplinary Technology Enhanced Care Pathway for Youth and Adults with Concussion
Published on: January 20, 2019
Impact of Interdisciplinary Team Care for Children With 22q11.2 Deletion Syndrome
Scott E Hickey1,2, Brian Kellogg3, Meghan O'Brien1
1Nationwide Children's Hospital, Columbus, OH, USA.
Insights
Multidisciplinary team care significantly improves guideline adherence for children with 22q11.2 deletion syndrome (22q11DS). This approach enhances care compared to standard treatment, highlighting its importance for managing this condition.
Area of Science:
- Genetics and Genomics
- Pediatric Healthcare
- Clinical Quality Improvement
Background:
- 22q11.2 deletion syndrome (22q11DS) is a complex genetic disorder requiring comprehensive, coordinated care.
- Adherence to disease-specific guidelines is crucial for optimizing health outcomes in children with 22q11DS.
- The impact of multidisciplinary team care on guideline adherence in this population has not been fully elucidated.
Purpose of the Study:
- To evaluate disease-specific guideline adherence in children with 22q11DS receiving multidisciplinary team care.
- To compare guideline adherence between children with 22q11DS receiving team care versus those not receiving team care.
- To assess the impact of a 22q specialty clinic visit on guideline adherence.
Main Methods:
- Retrospective chart review and quality improvement project conducted at a tertiary care pediatric hospital.
- One hundred eighty-nine patients with 22q11DS were divided into two groups: team care and non-team care.
- Guideline adherence was measured as the percentage adherence across 8 disease-specific guidelines.
Main Results:
- Mean guideline adherence was significantly higher in the team care group (83%) compared to the non-team care group (42%, P < .001).
- For patients receiving team care, adherence increased from 63% before a clinic visit to 86% six months post-visit (P < .001).
- Both provider and patient factors contributed to guideline nonadherence.
Conclusions:
- Multidisciplinary team care is strongly associated with improved guideline adherence in children with 22q11DS.
- Further research is warranted to explore the long-term health outcome benefits of team care for 22q11DS patients.
- Specialty clinics play a vital role in enhancing adherence to care guidelines for rare genetic conditions.
Objective:
To evaluate disease-specific guideline adherence among children with 22q11.2 deletion syndrome receiving multidisciplinary team care through a 22q specialty clinic compared to children not receiving team care.
Design:
Retrospective chart review; quality improvement project.
Setting:
Tertiary care pediatric hospital.
Patients:
One hundred eighty-nine patients with 22q11.2 deletion syndrome were categorized into those receiving team care and those not receiving team care. Guideline adherence was compared between the 2 groups.
Main Outcome Measure(S):
Percent adherence across 8 disease-specific guidelines.
Results:
A Welch t test revealed mean adherence among patients receiving team care was significantly higher (83% vs 42%, P < .001) compared those not receiving team care. Among team patients with a single 22q Center visit, a paired samples t test showed that mean adherence increased from 63% before the clinic encounter to 86% six months after the encounter (P < .001). Some guidelines were more likely to be associated with provider nonadherence, whereas others were more likely to be associated with patient nonadherence.
Conclusions:
Multidisciplinary team care is associated with significantly higher guideline adherence in children with 22q11DS. Additional research is needed to investigate the effect of team care on long-term health outcomes in children with 22q11DS.
Related Concept Videos
01:18Interdisciplinary Care: The Health Care Team-II
Physical Therapist
A physical therapist (PT) aims to restore function or prevent additional impairment in a patient following an injury or disease. Massage, heat, cold, water, sonar waves, exercises, and electrical stimulation are some treatments used by PTs to treat...
01:21Interdisciplinary Care: The Health Care Team-I
Physicians
The physician's primary responsibility is to diagnose illness and direct the medical or surgical treatment of the condition. The authority to admit patients to a healthcare agency or institution and practice care within that setting is granted to physicians by the healthcare agency or institution...
01:28Chronic Kidney Disease III: Interprofessional Care
01:20Acute Kidney Injury V: Interprofessional Care
01:26Aneurysm III: Interprofessional Care
01:29Cardiomyopathy V: Interprofessional Care