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Related Experiment Video

Updated: Dec 12, 2025

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Technical implementation of percutaneous thrombus aspiration using the AngioVac system.

Benjamin Haupt1,2, Frank Merkle2,3, Thomas Dreizler1

  • 1Department of Perfusion, German Heart Center Berlin, Berlin, Germany.

Perfusion
|August 14, 2020
PubMed
Summary

The AngioVac system safely removes thrombi and lead vegetations using minimally invasive aspiration. This study details initial experiences and circuit improvements for enhanced usability and safety in venous procedures.

Keywords:
AngioVac systempacemaker lead thrombosispulmonary embolismvacuum-assisted thrombectomy

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Area of Science:

  • Cardiovascular Interventions
  • Medical Device Technology
  • Vascular Surgery

Background:

  • Central venous thrombi, lead vegetations, and right atrial thrombi pose significant clinical challenges.
  • Minimally invasive techniques are increasingly preferred for managing complex venous obstructions.
  • Existing aspiration systems may have limitations in efficacy and safety.

Purpose of the Study:

  • To evaluate the initial clinical experience with the AngioVac system for percutaneous aspiration.
  • To describe the development and implementation of an improved extracorporeal circuit for the AngioVac system.
  • To assess the safety and efficacy of the AngioVac system in removing venous thrombi and vegetations.

Main Methods:

  • Retrospective observational study of 52 adult patients undergoing percutaneous aspiration with the AngioVac system.
  • Focus on modifications to the extracorporeal circuit to enhance usability and safety.
  • Analysis of procedural success rates and complications.

Main Results:

  • Successful aspiration in 84.6% of cases (44/52 patients).
  • Indications included lead vegetations (69.2%), right atrial thrombi (17.3%), and central venous thrombi (9.6%).
  • Improvements included a shunt line for recirculation and enhanced air handling safety features.

Conclusions:

  • The AngioVac system demonstrated safety in its initial application for extracorporeal circulation.
  • The system effectively eliminated thrombi and lead vegetations in the majority of cases.
  • Further validation on a larger scale is warranted for pressure monitoring.