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Chronic obstructive pulmonary disease.

N R Anthonisen1

  • 1Section of Respiratory Disease, University of Manitoba, Winnipeg.

CMAJ : Canadian Medical Association Journal = Journal De L'Association Medicale Canadienne
|March 15, 1988
PubMed
Summary
This summary is machine-generated.

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Effective outpatient management of chronic obstructive pulmonary disease (COPD) involves bronchodilators for most patients. Other treatments like antibiotics and oxygen are reserved for specific symptoms or conditions like hypoxemia.

Area of Science:

  • Pulmonology
  • Internal Medicine

Background:

  • Chronic obstructive pulmonary disease (COPD) management in outpatient settings requires a nuanced approach.
  • Established treatments and their efficacy in COPD require ongoing review.

Purpose of the Study:

  • To review current strategies for outpatient management of chronic obstructive pulmonary disease (COPD).
  • To evaluate the efficacy and indications for various therapeutic interventions in COPD patients.

Main Methods:

  • Literature review of studies on COPD outpatient management.
  • Analysis of evidence for pharmacological and non-pharmacological interventions.

Main Results:

  • Bronchodilator therapy, particularly beta 2-agonists, is indicated for most COPD patients.

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  • Antibiotics are beneficial for symptomatic exacerbations; systemic corticosteroids are for a subset of patients.
  • Continuous oxygen therapy is crucial for chronic arterial hypoxemia; cor pulmonale management involves diuretics and oxygen.

    • Conclusions:

    • Bronchodilators offer significant benefits beyond symptom relief in COPD.
    • Targeted use of antibiotics, corticosteroids, and oxygen therapy is essential for managing COPD exacerbations and complications.
    • Smoking cessation importance is noted, though benefit in established COPD is unproven.