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Normative data for the EORTC QLQ-C30 from the Austrian general population.

Jens Lehmann1, Johannes M Giesinger2, Sandra Nolte3,4

  • 1University Hospital of Psychiatry II, Medical University of Innsbruck, Anichstrasse 35, 6020, Innsbruck, Austria. jens.lehmann@i-med.ac.at.

Health and Quality of Life Outcomes
|August 14, 2020
PubMed
Summary

This study provides Austrian normative data for the European Organisation for Research and Treatment of Cancer (EORTC) Quality of Life Questionnaire-Core 30 (QLQ-C30). These findings aid in interpreting cancer patient quality of life scores in Austria.

Keywords:
AustriaEORTC QLQ-C30General populationNormative dataOncologyPatient-reported outcome measuresQuality of life

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Area of Science:

  • Health Services Research
  • Psychometrics
  • Oncology

Background:

  • The European Organisation for Research and Treatment of Cancer (EORTC) Quality of Life Questionnaire-Core 30 (QLQ-C30) is a key tool for assessing cancer patient health-related quality of life (HRQoL).
  • Interpreting QLQ-C30 scores requires relevant normative data, which was lacking for the Austrian general population.

Purpose of the Study:

  • To establish Austrian normative data for the EORTC QLQ-C30 questionnaire.
  • To facilitate the interpretation of QLQ-C30 scores in Austrian cancer patients and research.

Main Methods:

  • Utilized data from 1002 Austrian participants in an international online panel study.
  • Calculated normative data for all 15 HRQoL domains, stratified and weighted by age and sex.
  • Developed a regression model incorporating sex, age, and health conditions for precise score prediction.

Main Results:

  • Men reported better physical and emotional functioning, less fatigue, and less insomnia than women.
  • Younger individuals (<40 years) reported less dyspnea and pain.
  • Older individuals (≥60 years) reported better emotional functioning.

Conclusions:

  • Presented Austrian normative data for the EORTC QLQ-C30, aligning with other European studies.
  • The Austrian sample exhibited higher HRQoL and lower morbidity compared to other European populations.
  • These normative data will enhance the interpretation of QLQ-C30 scores in clinical oncology and research, supporting national and international comparisons.