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COVID-19-associated apnea and circumoral cyanosis in a 3-week-old

Joseph S Needleman1, Amy E Hanson2

  • 1Internal Medicine-Pediatrics Residency Program, Indiana University School of Medicine, 705 Riley Hospital Drive, Rm 5837, Indianapolis, IN, 46202, USA. jsneedle@iu.edu.

BMC Pediatrics
|August 14, 2020
PubMed

Insights

This case report details a three-week-old infant with COVID-19 presenting with apnea and perioral cyanosis. This highlights a new presentation of coronavirus disease 2019 in infants, emphasizing the need for testing.

Area of Science:

  • Neonatal Medicine
  • Pediatric Infectious Diseases
  • Virology

Background:

  • Limited data exists on coronavirus disease 2019 (COVID-19) in infants.
  • Infant COVID-19 cases and outcomes require further investigation.

Observation:

  • A three-week-old infant with hypoxic ischemic encephalopathy (HIE) history presented with recurrent apnea and perioral cyanosis.
  • The infant tested positive for COVID-19 and negative for other common respiratory viruses during both hospital admissions.

Findings:

  • This is the first reported case of apnea and perioral cyanosis associated with COVID-19 in an infant.
  • The presentation suggests a novel manifestation of COVID-19 in the pediatric population.

Implications:

  • This case underscores the importance of considering COVID-19 in infants presenting with respiratory distress.
  • Early viral diagnostic testing is crucial for mildly symptomatic infants to prevent disease transmission.
  • Further research is needed to understand the full spectrum of COVID-19 in neonates and infants.
Abstract

Keywords:
ApneaBRUECOVID-19ChildrenCyanosisInfantNeonatePediatricsSARS-CoV-2

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