Related Experiment Video
Updated: Dec 12, 2025

06:24
Establishment of Rat Models Mimicking Gender-affirming Hormone Therapies
Published on: January 10, 2025
1.2K
Technology-Based Stepped Care to Stem Transgender Adolescent Risk Transmission: Protocol for a Randomized Controlled
Cathy J Reback1,2, Joshua A Rusow1, Demetria Cain3
1Friends Research Institute, Inc, Los Angeles, CA, United States.
JMIR Research Protocols
|August 14, 2020
Summary
This study tested technology-based interventions, including text messaging and WebApp, to reduce sexual risk behaviors and increase pre-exposure prophylaxis (PrEP) uptake in transgender youth. Results will inform tailored, scalable HIV prevention strategies.
Area of Science:
- Public Health
- Intervention Science
- Digital Health
Background:
- Transgender youth face higher HIV risks due to syndemic disparities like sexual risk behaviors and abuse.
- These disparities necessitate targeted HIV prevention strategies for this vulnerable population.
Purpose of the Study:
- To evaluate the immediate and sustained effects of text messaging, WebApp, and information-only interventions.
- To reduce sexual risk behaviors and increase pre-exposure prophylaxis (PrEP) uptake among high-risk, HIV-negative transgender youth and young adults (15-24 years).
Main Methods:
- A randomized controlled trial (RCT) involving 250 participants.
- Interventions included text messaging, WebApp, or an information-only control for 6 months.
- Rerandomization for enhanced support (eCoaching) was offered if initial interventions were ineffective.
Main Results:
- Recruitment for Phase 2 (RCT) began in November 2018, with data collection expected to conclude in April 2021.
- As of March 2020, 54 participants were enrolled.
- Final results are anticipated in May 2021.
Conclusions:
- Culturally responsive, technology-based interventions can improve sexual health outcomes for transgender youth.
- TechStep evaluates the efficacy of digital interventions for reducing HIV risk and increasing PrEP use.
- This study advances intervention science for developing scalable HIV prevention tools for transgender youth.
Keywords:
HIVacquired immunodeficiency syndromemobile phonepre-exposure prophylaxistechnologytransgenderMore Related Videos
Related Concept Videos
Sexually Transmitted Infections
702
Sexually transmitted infections (STIs) are diseases transmitted primarily through unsafe sexual interactions. Bacteria, viruses, or parasites cause them and can result in severe health complications if untreated.ChlamydiaThe bacterium Chlamydia trachomatis is responsible for the disease Chlamydia, the most common STI in the United States. This peculiar pathogen requires human cells to reproduce, residing intracellularly. The initial infection often goes unnoticed because it typically does not...
702
Types of Biopharmaceutical Studies: Controlled and Non-Controlled Approaches
307
Biopharmaceutical studies constitute a vital field aiming to enhance drug delivery methods and refine therapeutic approaches, drawing upon diverse interdisciplinary knowledge. In research methodologies, the choice between controlled and non-controlled studies significantly influences the study's reliability and accuracy.
Non-controlled studies, commonly employed for initial exploration, lack a control group, rendering them susceptible to biases and external influences. In contrast,...
Non-controlled studies, commonly employed for initial exploration, lack a control group, rendering them susceptible to biases and external influences. In contrast,...
307

