Related Experiment Video
Updated: Dec 12, 2025

Author Spotlight: Unveiling the Connection Between Sleep Disorders and Cognitive Symptoms in Depression
Published on: April 26, 2024
Risk factors for possible REM sleep behavior disorders: A community-based study in Beijing
Hui Zhang1, Zhuqin Gu1, Chun Yao1
1From the Department of Neurology and Neurobiology, National Clinical Research Center for Geriatric Disorders (H.Z.), Department of Neurobiology, Key Laboratory of Ministry of Education for Neurodegenerative Diseases (Y.C.), and Department of Neurology (Y.L., W.M., E.X.), Xuanwu Hospital of Capital Medical University (P.C.); Key Laboratory of Ministry of Education for Neurodegenerative Diseases (Z.G.) and Department of Neurology, Neurobiology, and Geriatrics, National Clinical Research Center for Geriatric Disorders, Clinical and Research Center for Parkinson's Disease (P.C.), Parkinson Disease Center of Beijing Institute for Brain Disorders, Beijing Key Laboratory on Parkinson's Disease, China; Integrated Program in Neuroscience (C.Y.), McGill University; and Department of Neurology (R.B.P.), Montreal General Hospital, Canada.
This study identified key risk factors for REM sleep behavior disorder (RBD) in older adults, including a family history of parkinsonism, hyperlipidemia, smoking, pesticide exposure, and carbon monoxide poisoning.
Area of Science:
- Neurology
- Sleep Medicine
- Epidemiology
Background:
- Idiopathic REM sleep behavior disorder (RBD) is a neurodegenerative disease precursor.
- Understanding risk factors is crucial for early detection and intervention.
Purpose of the Study:
- To investigate environmental, lifestyle, and other potential risk factors for idiopathic REM sleep behavior disorder (RBD) in a community-based elderly population in Beijing.
Main Methods:
- Recruited 7,225 participants aged 55+ from the Beijing Longitudinal Study on Aging II.
- Identified possible RBD (pRBD) using the RBD Questionnaire-Hong Kong.
- Assessed risk factors via questionnaires and analyzed associations using multivariable logistic regression.
Main Results:
- 3.0% of participants had pRBD.
- pRBD was associated with nonmotor and motor symptoms of Parkinson disease (PD).
- Significant associations found with family history of parkinsonism/dementia, hyperlipidemia, smoking, CO poisoning, and pesticide exposure.
Conclusions:
- Replicated known associations for pRBD (hyperlipidemia, smoking, pesticides, prodromal PD symptoms).
- Identified novel links between pRBD and family history of parkinsonism/dementia, and CO poisoning.
- RBD risk factors partially overlap with PD but have distinct elements.
More Related Videos
06:23A Chronic Sleep Fragmentation Model using Vibrating Orbital Rotor to Induce Cognitive Deficit and Anxiety-Like Behavior in Young Wild-Type Mice
Published on: September 22, 2020
05:59Author Spotlight: Overcoming Challenges in Drosophila Sleep Measurement Using DAM System
Published on: October 20, 2023
Related Concept Videos
REM Sleep Behavior Disorder
RBD is significantly associated with...
Insufficient Sleep and Sleep Deprivation
Sleep deprivation is a more severe form of sleep loss...
Sleep-Wake Cycles
NREM Sleep
NREM sleep comprises four progressive stages that seamlessly merge:
Substance Use Disorders Affecting Sleep
Understanding the concepts of physical dependence,...
Narcolepsy
Sleepwalking and Sleep Talking
Factors that increase the likelihood of sleepwalking include sleep deprivation and alcohol consumption. Contrary to common beliefs, it is safe...