[Treatment with Chloranphenicol of neonatal sepsis-meningitis by gram-negative bacteria (author's transl)]

Eight newborn infants having previously received broad spectrum antibiotics were treated with intravenous chloranphenicol succinate for sepsis-meningitis during a klebsiella neumoniae outbreak. Five of them survived without sequelae. Over the third week of treatment two infants developed a transient bone marrow suppresion accompanied by a "pseudo-septic" clinical picture; this syndrome, that we have not found previously reported, was benign, disappearing when the drug was discontinued.