Related Experiment Video
Updated: Dec 12, 2025

Isolating Human Peripheral Blood Mononuclear Cells and CD4+ T cells from Sézary Syndrome Patients for Transcriptomic Profiling
Published on: October 14, 2021
Polymorphic Eruption of Extensive Cutaneous Sarcoidosis
Payal Chauhan1, Dilip Meena2, Naveen Kumar Kansal2
1Department of Dermatology, Venereology and Leprology, All India Institute of Medical Sciences, Rishikesh, India; chauhanpayal89@gmail.com.
Abstract:
A 40-year-old man presented with a 1-year history of asymptomatic multiple raised reddish lesions that started on the face and gradually progressed in size and number to involve the neck, trunk, and arms. There was no history of fever, fatigue, weight loss, arthralgia, cough, dyspnea, or ocular complaints. Past and family history was insignificant, and no significant drug history could be elicited. On examination, multiple reddish brown, shiny, firm papuloplaques and nodules were present over the face, neck, and arms. There was a reddish brown plaque with central depression and overlying prominent telangiectasia over the left perioral area. The lesions over the posterolateral aspects of the arms were atrophic with peripheral reddish brown papules and central clearing, assuming an annular configuration. There were multiple large indurated subcutaneous and atrophic plaques over the arm and back. The palms, soles, hair, nail, and mucosal areas were not involved.
Related Concept Videos
Skin Cancer
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
Skin Diseases and Disorders
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
Papillary Dermis
The dermis might be considered the "core" of the integumentary system, as distinct from the epidermis and hypodermis. It contains blood and lymph vessels, nerves, and other structures, such as hair follicles and sweat glands. The dermis is made of two layers of connective tissue that comprise an interconnected mesh of elastin and collagenous fibers, produced by fibroblasts.
Papillary Layer
The papillary layer is made of loose, areolar connective tissue, which means the collagen...
Pulmonary Tuberculosis III
The first classification is based on the development of the disease, and it includes the following categories:
Reticular Dermis
Reticular Layer
Underlying the papillary layer is the much thicker reticular layer, composed of dense, irregular connective...
Pulmonary Tuberculosis II
Here is a detailed explanation of its pathophysiology:
Transmission: The process begins when a person inhales droplet nuclei containing M. tuberculosis. These are typically released into the air when an individual with pulmonary or...

