[Eccrine porocarcinoma of the nose with cervical metastasis：a case report]

An 18-year-old man presented with a slow-growing, painful mass on the nasal dorsum that first appeared 4 years earlier. Clinical examination revealed a 5 cm×6 cm, claret-coloured, firm, nonmobile mass on the dorsum of the nose with superficial ulceration and purulent discharge. After several operations, radiotherapy and chemotherapy, no nasal recurrence was found, but recurrence of metastatic masses in the neck. Histopathologic examination showed that the neoplasms were solid nests with adenoid and squamous differentiation. Immunohistochemical result showed that EMA（－）, CEA（－）, p16（+）, p53（+）, Ki-67 progressive heighten. The disease is rare, and clinical manifestations are nonspecific. Diagnosis depends on histopathological examination. Ki-67 can be used as a reference index to judge the degree of EPC malignancy. Expanded early excision should be performed. Patient with cervical metastasis had a poor prognosis. Radiotherapy and chemotherapy were ineffective.