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Neuromuscular electrical stimulation for cancer pain in children with osteosarcoma: A protocol of systematic review
Tian-Shu Wang1, Shou-Feng Wang2, Wei-Dong Song3
1Second Ward of Orthopedis Department.
Insights
This systematic review examines if neuromuscular electrical stimulation (NMES) effectively and safely manages cancer pain (CP) in children with osteosarcoma. Findings will guide treatment decisions for pediatric osteosarcoma pain.
Area of Science:
- Oncology
- Pain Management
- Rehabilitation
Background:
- Osteosarcoma is a primary bone cancer in children, often associated with significant cancer pain (CP).
- Current pain management strategies for pediatric osteosarcoma require comprehensive evaluation.
- Neuromuscular electrical stimulation (NMES) is a potential non-pharmacological intervention for pain relief.
Purpose of the Study:
- To systematically review the effectiveness of NMES in managing cancer pain (CP) in pediatric osteosarcoma patients.
- To assess the safety profile of NMES when used for CP in this population.
- To synthesize existing evidence to inform clinical practice.
Main Methods:
- A systematic review protocol was established, searching multiple electronic databases (Cochrane Library, MEDLINE, EMBASE, Web of Science, Scopus, CNKI, VIP).
- Eligibility criteria were applied through a three-stage screening of titles, abstracts, and full-text studies.
- Study quality was assessed using the Cochrane Risk of Bias Tool, with plans for narrative synthesis and meta-analysis.
Main Results:
- This review will synthesize findings from high-quality trials evaluating NMES for cancer pain (CP) in pediatric osteosarcoma.
- The effectiveness and safety data from included studies will be critically appraised.
- Results will provide a comprehensive overview of NMES's role in managing this specific patient group.
Conclusions:
- The study aims to determine the efficacy and safety of NMES for cancer pain (CP) in children with osteosarcoma.
- Evidence generated will support or refute the use of NMES as a viable treatment option.
- Findings will contribute to evidence-based guidelines for pediatric oncology pain management.
Background:
This systematic review will assess the effectiveness and safety neuromuscular electrical stimulation (NMES) for cancer pain (CP) in children with osteosarcoma.
Methods:
This systematic review protocol will retrieve the following electronic databases from inception to June 1 in Cochrane Library, MEDLINE, EMBASE, Web of Science, Scopus, CNKI, and VIP database. Manual head-searching of reference lists and conference proceedings will be performed to further examine the articles of interest. No restrictions will be applied to language and publication status. We will utilize a 3-stage approach to scan titles, abstracts, and full-text studies against all eligibility criteria, and collect data from included trials. Study quality will be evaluated by the Cochrane Risk of Bias Tool. If possible, we will narratively summarize study results and carry out meta-analysis.
Results:
This study will recapitulate the present high quality trials to appraise the effectiveness and safety of NMES for CP in children with osteosarcoma.
Conclusion:
The findings of this study will present evidence to determine whether NMES is effective and safe for CP in children with osteosarcoma.
