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Updated: Dec 12, 2025

Normothermic Negative Pressure Ventilation Ex Situ Lung Perfusion: Evaluation of Lung Function and Metabolism
Published on: February 14, 2022
Negative pressure ventilation as a bridge to lung transplant
María D P Martínez1, Francisco G Alvarez1, Jorge M Mallea2
1Department of Transplantation, Mayo Clinic, Jacksonville, FL 32224 USA.
Abstract:
Recent years have witnessed evolution of lung allocation strategies to prioritize sicker recipients. In the pre-transplant period, this has translated into increased utilization of invasive extracorporeal or mechanical ventilatory support as a bridge to lung transplantation. The morbidity associated with these strategies warrants consideration to less invasive respiratory support modalities. Herein, we present a case highlighting successful bridge to lung transplantation with a relatively non-invasive negative pressure ventilator.
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