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Published on: January 28, 2020
Clinical characteristics and factors associated with coronary stenosis proximal to a myocardial bridge: a
Wen Gao1, Jiaxi Zhang2, Fei Duan3
1First Department of Cardiology, Bayannaoer City Hospital, No. 98 Wulan Buhe Road, Linhe District, Bayannaoer City, 015000, Inner Mongolia Autonomous Region, China.
Insights
Myocardial bridges (MB) in the middle or distal left anterior descending artery (LAD) are independently linked to coronary stenosis. This finding clarifies risk factors for patients with MB and cardiovascular symptoms.
Area of Science:
- Cardiology
- Vascular Biology
- Medical Imaging
Background:
- The relationship between myocardial bridges (MB) and cardiovascular risk factors is not well understood.
- Investigating the clinical characteristics and associated factors of coronary stenosis near MB is crucial.
Purpose of the Study:
- To explore the clinical characteristics of coronary stenosis proximal to myocardial bridges.
- To identify factors associated with coronary stenosis in patients with MB.
Main Methods:
- Retrospective study of 244 patients with MB and cardiovascular symptoms undergoing selective coronary angiography (SCAG).
- Patients were categorized into non-stenosis and stenosis groups based on coronary stenosis presence proximal to MB.
- Multivariable analysis was used to identify independent risk factors.
Main Results:
- 91 patients (37.3%) had stenosis proximal to MB.
- The stenosis group had a higher proportion of males and smokers compared to the non-stenosis group.
- MB located in the middle distal or distal LAD was independently associated with coronary stenosis proximal to MB (OR=0.439, P=0.002).
Conclusions:
- Myocardial bridges located in the middle distal or distal LAD are independently associated with coronary stenosis.
- This finding helps in understanding the specific anatomical locations of MB that increase cardiovascular risk.
Background:
The association of myocardial bridge (MB) with cardiovascular risk and the possible cardiovascular risk factors remain unclear. This study aimed to explore the clinical characteristics and related factors of coronary stenosis proximal to an MB.
Methods:
This was a retrospective study of patients with symptoms of coronary atherosclerotic heart disease admitted between 10/2011 and 12/2014 to the Emergency and Cardiology Department of Bayannur Hospital, who underwent selective coronary angiography (SCAG). The patients were assigned to the non-stenosis and stenosis groups according to whether coronary stenosis was proximal to the MB.
Results:
Among 244 patients with MB and cardiovascular symptoms, 91 (37.3%) had stenosis proximal to the MB. Compared with the non-stenosis group, there were more males (80.2% vs. 55.6%, P < 0.001) and smokers (including those who had quit smoking) (P < 0.001) in the stenosis group. There were no significant differences in blood lipid-related indexes (TG, TC, HDL-C, LDL-C, and VLDL-C) between the two groups. Multivariable analysis suggested that MB location in the middle distal or distal segment of the left anterior descending artery (LAD) increased the odds of coronary stenosis proximal to the MB (OR = 0.439, 95% CI: 1.57-7.532, P = 0.002), which was then considered an independent factor associated with coronary stenosis proximal to the MB.
Conclusions:
In patients diagnosed with an MB by SCAG, only MB located in the middle distal or distal segment of the LAD is independently associated with coronary stenosis proximal to the MB.
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