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GATA6-AS1 Regulates GATA6 Expression to Modulate Human Endoderm Differentiation

Jie Yang1, Pei Lu1, Mao Li1

  • 1Department of Biological Repositories, Frontier Science Center for Immunology and Metabolism, Medical Research Institute, Zhongnan Hospital of Wuhan University, Wuhan University, Wuhan 430071, China.

Stem Cell Reports
|August 16, 2020
PubMed
Summary

Long noncoding RNA GATA6-AS1 is crucial for human endoderm development. It activates the key gene GATA6 by interacting with SMAD2/3, ensuring proper cell differentiation.

Keywords:
GATA6GATA6-AS1SMAD2/3human endodermhuman pluripotent stem cellslong noncoding RNA

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