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Area of Science:

  • Ophthalmology
  • Pharmacology
  • Natural Products

Background:

  • Allergic conjunctivitis and dry eye syndrome are prevalent ocular surface diseases.
  • Traditional treatments like corticosteroids and antihistamines have potential side effects.
  • There is growing interest in complementary and integrative medicine for ocular conditions.

Purpose of the Study:

  • To evaluate the anti-inflammatory and antiallergic effects of flavonoids and cannabinoids.
  • To assess their impact on the anterior surface of the eye.
  • To explore their potential as complementary treatments for ocular surface disorders.

Main Methods:

  • Review of existing research on flavonoids (e.g., quercetin, catechin, pycnogenol, epigallocatechin gallate) and cannabinoids.
  • Investigation of topical and systemic application methods.
  • Consideration of research on ocular cannabinoid receptors.

Main Results:

  • Flavonoids and their derivatives have shown efficacy in alleviating dry eye symptoms and inflammation.
  • Cannabinoids are being explored for therapeutic responses in anterior ocular disorders.
  • Herbal formulations are expanding as a framework for future treatments.

Conclusions:

  • Flavonoids and cannabinoids demonstrate potential as complementary treatments for allergic eye diseases.
  • These compounds possess anti-inflammatory and antiallergic properties.
  • Ocular and systemic applications may serve as adjuvant strategies to improve patient quality of life and manage ocular surface disease.