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Incidental Metastatic Melanoma Identified on 18F-FDOPA PET/CT With Confirmation by Histology
Jules Zhang-Yin1, Christel Jublanc2, Iman Aouidad3
1From the Department of Nuclear Medicine, Hôpital Tenon & Sorbonne Université.
Abstract:
A 47-year-old woman with a history of surgically treated abdominal paraganglioma and left thigh melanoma underwent an F-FDOPA PET/CT for suspected locoregional recurrence of paraganglioma. F-FDOPA PET/CT disconfirmed this recurrence but revealed 2 FDOPA-avid left inguinal lymph nodes, confirmed on a subsequent F-FDG PET/CT. Excision and pathology characterized these lymph nodes as melanoma metastases. F-FDOPA PET/CT is a widely used and valuable tool in the assessment of paraganglioma, both for staging and recurrence detection. Uptake of FDOPA has only rarely been documented in metastatic melanoma that could be a pitfall for detecting neuroendocrine tumors.
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