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Published on: June 2, 2014
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Migraine and menopause - a narrative review
Carolyn Bernstein1, Mary A O'Neal
1Department of Neurology; Brigham and Women's Hospital, Boston, MA.
Menopause (New York, N.Y.)
|August 16, 2020
Summary
Migraine prevalence may change during perimenopause, and while stroke risk with hormone therapy (HT) is small, HT can be a preventative treatment for migraine in menopausal women.
Area of Science:
- Neurology
- Gynecology
- Women's Health
Background:
- Migraine is a prevalent neurological condition affecting many women.
- The perimenopausal transition significantly impacts migraine patterns and management.
- Understanding these changes is crucial for both patients and physicians.
Purpose of the Study:
- To review the effect of perimenopause on migraine prevalence and type.
- To assess the stroke risk associated with migraine and hormone therapy (HT).
- To outline best practices for migraine treatment in perimenopausal women.
Main Methods:
- Narrative review of clinical questions regarding migraine during perimenopause.
- Systematic literature search of PubMed (2010-present) using keywords: migraine, menopause, HT.
- Inclusion of English full-text articles and key references from search results.
Main Results:
- Migraine prevalence may shift during perimenopause, though a definitive timeline for postmenopausal resolution is not established.
- Stroke risk in women with migraine with aura is low but population-level significant; HT's impact on this risk is minimal.
- Hormone therapy (HT) is a recognized preventative treatment for female migraineurs during the menopausal transition.
Conclusions:
- Migraine management requires tailored approaches during the perimenopausal transition.
- While HT poses a small stroke risk, it remains a viable preventative option for migraine.
- Further research is needed on sex-specific responses to conventional migraine treatments in this demographic.
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