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Updated: Dec 11, 2025

An Intact Pericardium Ischemic Rodent Model
Published on: September 2, 2021
Update on diagnosis and management of neoplastic pericardial disease
Stefano Avondo1, Alessandro Andreis1, Matteo Casula1
1Cardiovascular and Thoracic Department, University Cardiology, AOU Città Della Salute e Della Scienza Di Torino , Torino, Italy.
Introduction:
Pericardial neoplasms are uncommon, mostly due to secondary involvement of the pericardium by extracardiac tumors. Clinical presentation is nonspecific, frequently leading to a delayed diagnosis. Moreover, both benign and malignant pericardial tumors may be associated with myocardial infiltration and mechanical compression of cardiac chambers, possibly precipitating clinical conditions. Pericardial tumors are indeed a diagnostic and therapeutic clinical challenge.
Areas Covered:
This review aims to provide an overview of the main clinical characteristics of pericardial tumors, along with their management in clinical practice.
Expert Commentary:
Multimodality imaging (echocardiography, chest X-ray, CT, CMR, and PET) enable full characterization of pericardial neoplasms. An individualized strategy should be developed by a multidisciplinary team including cardiologists, oncologists, radiologists, and cardiac surgeons.
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