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Updated: Dec 11, 2025

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Upper-extremity Approach for Secondary Access in Transfemoral Transcatheter Aortic Valve Implantation
Published on: August 8, 2025
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Infective endocarditis following transcatheter aortic valve implantation.
Summary
Trans-catheter aortic valve implantation (TAVI) is a less invasive option for high-risk patients. However, infective endocarditis (TAVI-IE) is a rare but serious complication, posing treatment challenges and high mortality rates.
Area of Science:
- Cardiology
- Infectious Diseases
- Surgical Innovation
Background:
- Trans-catheter aortic valve implantation (TAVI) offers a less invasive alternative to surgical aortic valve replacement (SAVR) for high-risk patients.
- Infective endocarditis (IE) is a rare but life-threatening complication following TAVI procedures.
Observation:
- TAVI-associated infective endocarditis (TAVI-IE) presents significant treatment challenges.
- Conservative antibiotic therapy for TAVI-IE is associated with high mortality (40%).
- Surgical explant, while definitive, carries substantial risks, including 87% complication rates and 47% in-hospital mortality.
Findings:
- This paper reports a case of a 71-year-old patient experiencing early endocarditis after TAVI (TAVI-IE).
- The patient was successfully treated with surgical explant at our institution.
Implications:
- The case highlights a critical dilemma in managing TAVI-IE in patients initially deemed high-risk for SAVR.
- It raises questions about the optimal treatment strategy for TAVI-IE in this vulnerable population.
- Further research is needed to establish best practices for TAVI-IE management, balancing risks and benefits.
Keywords:
Endocardite infectieuseImplantation transcathéter de valve aortiqueInfective endocarditisTrans-catheter aortic valve implantationMore Related Videos
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