Transfusion-associated babesiosis in China: A case report

Babesiosis, a novel zoonosis, is endemic in the Northeast and Midwest United States. This disease is primarily transmitted by ticks and less commonly transmitted through blood transfusion. Here, we present a case of human babesiosis of unknown etiology. The patient may have been infected through blood transfusion. This patient had fever for more than 1 month, accompanied by fatigue, anemia, jaundice, and other symptoms. Clinical improvement was unsatisfactory with antibiotics. Subsequently, peripheral blood smears showed many circulating forms of parasites,morphologically consistent with Babesia in red blood cells. Gene sequencing suggested Babesia microti. We treated the patient with azithromycin combined with other symptomatic supportive treatment. Finally, the patient recovered and was discharged. The intensity of babesiosis ranges from mild to severe and can be fatal, so early diagnosis and treatment are warranted.