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Surgical Therapies for Chronic Obstructive Pulmonary Disease
Sean Duffy1, Nathaniel Marchetti1, Gerard J Criner1
1Department of Thoracic Medicine and Surgery, Lewis Katz School of Medicine at Temple University, 712 Parkinson Pavilion, 3401 North Broad Street, Philadelphia, PA 19140, USA.
Clinics in Chest Medicine
|August 18, 2020
Summary
Surgical options like lung volume reduction surgery and bullectomy can improve outcomes for severe chronic obstructive pulmonary disease patients. Lung transplantation is an option for advanced cases ineligible for other treatments.
Area of Science:
- Pulmonary Medicine
- Thoracic Surgery
Background:
- Severe chronic obstructive pulmonary disease (COPD) poses significant challenges.
- Maximal medical therapy and bronchoscopic interventions may not suffice for all patients.
Purpose of the Study:
- To outline surgical options for severe COPD patients.
- To identify patient subgroups who benefit from specific surgical interventions.
Main Methods:
- Review of surgical interventions for severe COPD.
- Analysis of patient selection criteria for lung volume reduction surgery, bullectomy, and lung transplantation.
Main Results:
- Lung volume reduction surgery benefits selected patients with upper lobe-predominant emphysema, especially those with low exercise performance.
- Bullectomy improves outcomes for patients with large bullae compressing lung tissue.
- Lung transplantation is a viable option for advanced COPD patients without major comorbidities.
Conclusions:
- Surgical interventions offer valuable therapeutic options for severe COPD.
- Careful patient selection is crucial for optimizing outcomes in lung volume reduction surgery and bullectomy.
- Lung transplantation provides a survival advantage for select end-stage COPD patients.
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