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Updated: Dec 11, 2025

In Vitro Assay of Plasmodium-Infected Red Blood Cell Killing by Cytotoxic Lymphocytes
Published on: August 17, 2022
RIFINing Plasmodium-NK Cell Interaction
Didier Ménard1, Sandrine Houzé2, Nicolas Papon3
1Unité Génétique du Paludisme et Résistance, Département de Parasites et Insectes Vecteurs, Institut Pasteur, Paris, France.
Abstract:
Among many Plasmodium proteins involved in the erythrocytic cycle, some exposed on the erythrocyte surface drive antigenic variability. Recently, Harrison et al. elucidated the structural basis by which RIFINs activate LILRB1 and suppress immune cell function. This breakthrough points to an additional strategy for survival in the human host.
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