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Acute and Post-Traumatic Stress Disorders: A biased nervous system
C Allene1, K Kalalou1, F Durand1
1Unité de recherche clinique, établissement public de santé Ville-Evrard, 202, avenue Jean-Jaurès, 93332 Neuilly-sur-Marne, France; Centre de psychothérapie, établissement public de santé Ville-Evrard, 5, rue du Docteur-Delafontaine, 93200 Saint-Denis, France.
Revue Neurologique
|August 18, 2020
Summary
Intense threats can disrupt brain circuits, leading to acute stress disorder and post-traumatic stress disorder. This study explains the neurobiology of trauma from neuron to behavior.
Area of Science:
- Neuroscience
- Psychology
- Trauma Studies
Background:
- Acute stress disorder and post-traumatic stress disorder arise from exceptionally intense traumatic events.
- Trauma can disrupt the balance between the brain's defensive and cognitive circuits.
Purpose of the Study:
- To explore the chronological consequences of traumatogenic situations.
- To provide a detailed explanatory model of trauma's underlying neurobiological mechanisms.
Main Methods:
- Analysis of neurobiological mechanisms from neuronal to behavioral scales.
- Chronological exploration of trauma progression from threat exposure to symptom development.
Main Results:
- Trauma disrupts the equilibrium between defensive (stress response, implicit memory) and cognitive (voluntary response, explicit memory) circuits.
- Overactivation of the defensive circuit can lead to its deactivation and dissociation in severe cases.
Conclusions:
- The study presents a comprehensive neurobiological model explaining trauma development.
- Understanding these mechanisms is crucial for addressing stress and trauma-related disorders.
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