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A Novel Stretching Platform for Applications in Cell and Tissue Mechanobiology
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The effect of mechanical stress on soft and hard tissue repair; a review

J D Urschel1, P G Scott, H T Williams

  • 1Department of Surgery, Faculty of Medicine, University of Alberta, Edmonton, Canada.

British Journal of Plastic Surgery
|March 1, 1988
PubMed

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Cell-matrix's Response to Mechanical Forces01:13

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In animal cells, the extracellular matrix allows cells within tissues to withstand external stresses and transmits signals from the outside of the cell to the inside. The extracellular matrix is extensive, and its composition varies between different types of tissues. For example, the reticular fibers and ground substance make up the ECM in loose connective tissue, while collagen and bone minerals make up the ECM of bone tissue. 
Anchoring junctions mechanically attach a cell to the...