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Utilization of Radiographic Imaging for Infant Hydronephrosis over the First 12 Months of Life
Anthony J Schaeffer1, Patrick C Cartwright1, Glen A Lau1
1Division of Urology, Department of Surgery, University of Utah, Salt Lake City, UT, USA.
Insights
Imaging use for infant hydronephrosis (HN) is directly related to its initial severity. This study suggests a risk-stratified approach to imaging for HN in infants, with more severe cases receiving more frequent imaging studies.
Area of Science:
- Pediatric Urology
- Radiology
- Healthcare Management
Background:
- Infant hydronephrosis (HN) management varies, potentially influenced by imaging intensity based on HN grade.
- A standardized approach to workup and surveillance is needed for optimal patient outcomes.
Purpose of the Study:
- To determine the frequency of imaging studies for infant hydronephrosis within the first year of life.
- To stratify imaging use by the initial grade of hydronephrosis in a large healthcare system.
Main Methods:
- Retrospective cohort study of infants born between 2005-2013 with confirmed hydronephrosis.
- Data collected included initial hydronephrosis grade, demographic information, and all HN-associated radiologic studies (ultrasound, VCUG, diuretic renal scans).
- Multivariate Poisson regression analyzed the association between initial HN grade and the total number of imaging studies within the first year or prior to pyeloplasty.
Main Results:
- Out of 1,380 infants, 72% had mild, 17% moderate, and 12% severe hydronephrosis.
- Infants with moderate and severe HN showed significantly higher rates of imaging use compared to those with mild HN (RR 1.57 and 2.09, respectively).
- Imaging frequency was proportional to the initial hydronephrosis grade after controlling for confounders.
Conclusions:
- Imaging utilization for infant hydronephrosis in this healthcare system is directly proportional to the initial grade of HN.
- This finding supports the use of a risk-stratified approach in managing infant hydronephrosis surveillance and workup.
- The study highlights a consistent, grade-dependent imaging strategy for pediatric hydronephrosis.
Purpose:
The workup and surveillance strategies for infant hydronephrosis (HN) vary, although this could be due to grade-dependent differences in imaging intensity. We aimed to describe the frequency of imaging studies for HN within the first year of life, stratified by initial HN grade, within a large regional healthcare system. Study Design and Data Source. Retrospective cohort using Intermountain Healthcare Data Warehouse. Inclusion criteria: (1) birth between 1/1/2005 and 12/31/2013, (2) CPT code for HN, and (3) ultrasound (U/S) confirmed HN within four months of birth. Data Collection. Grade of HN on initial postnatal U/S; number of HN-associated radiologic studies (renal U/Ss, voiding cystourethrograms (VCUGs), and diuretic renal scans); demographic and medical variables. Primary Outcome. Sum of radiologic studies within the first year of life or prior to pyeloplasty. Statistical Analysis. Multivariate poisson regression to analyze association between the primary outcome and the initial HN grade.
Results:
Of 1,380 subjects (993 males and 387 females), 990 (72%), 230 (17%), and 160 (12%) had mild, moderate, and severe HN, respectively. Compared with those with mild HN, patients with moderate (RR: 1.57; 95% CI: 1.42-1.73) and severe (RR: 2.09; 95% CI: 1.88-2.32) HN had a significantly higher rate of imaging use over 12 months (or prior to surgery) after controlling for potential confounders.
Conclusions:
In a large regional healthcare system, imaging use for HN is proportional to its initial grade. This suggests that within our system, clinicians treating this condition are using a risk-stratified approach to imaging.
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