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Updated: Dec 11, 2025

Stencil Micropatterning of Human Pluripotent Stem Cells for Probing Spatial Organization of Differentiation Fates
Published on: June 17, 2016
The recent advances in the mathematical modelling of human pluripotent stem cells
L E Wadkin1, S Orozco-Fuentes1, I Neganova2
1School of Mathematics Statistics and Physics, Newcastle University, Newcastle upon Tyne, UK.
Abstract:
Human pluripotent stem cells hold great promise for developments in regenerative medicine and drug design. The mathematical modelling of stem cells and their properties is necessary to understand and quantify key behaviours and develop non-invasive prognostic modelling tools to assist in the optimisation of laboratory experiments. Here, the recent advances in the mathematical modelling of hPSCs are discussed, including cell kinematics, cell proliferation and colony formation, and pluripotency and differentiation.
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