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Angle Closure Glaucoma: Treatment

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Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...

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[Acute angle-closure glaucoma and effusion syndrome after phacoemulsification].

M Anwar¹, T Brockmann², M Walckling²

¹Klinik und Poliklinik für Augenheilkunde, Universitätsmedizin Rostock, Doberaner Str. 140, 18057, Rostock, Deutschland. mahmoud.anwar@med.uni-rostock.de.

Der Ophthalmologe : Zeitschrift Der Deutschen Ophthalmologischen Gesellschaft

|August 18, 2020

Summary

Acetazolamide can cause rare but severe uveal effusion syndrome after cataract surgery. Prompt sulfonamide-free treatment led to rapid ocular improvement in a glaucoma patient.

Keywords:

Acetazolamide Adverse drug reaction Cataract surgery Sulfonamide allergy Uveal effusion syndrome

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Area of Science:

Ophthalmology
Pharmacology

Background:

Cataract surgery is a common procedure with potential complications.
Glaucoma and uveal effusion syndrome are serious ocular conditions.

Observation:

A 72-year-old female developed bilateral secondary angle-closure glaucoma with uveal effusion syndrome post-cataract surgery.
Acetazolamide, a sulfonamide medication, was identified as the likely cause.

Findings:

The patient experienced a rare adverse effect of acetazolamide.
Sulfonamide-free systemic and local treatments for intraocular pressure and inflammation were initiated.

Implications:

This case highlights a severe, albeit uncommon, side effect of acetazolamide.
Effective management involves prompt cessation of the causative agent and appropriate anti-glaucoma and anti-inflammatory therapies.